Ala Trusina

Ala Trusina

Associate Professor


  1. 2023
  2. Published

    A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation

    Knudsen, Teresa Emmilie Toudal, Hamilton, W. B., Proks, Martin, Lykkegaard, M., Linneberg-Agerholm, Madeleine, Nielsen, Alexander Valentin, Perera Pérez, Marta, Malzard, L. L., Trusina, Ala & Brickman, Joshua Mark, 2023, In: Cell Systems. 14, 9, p. 788-805.e8

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

    Unterweger, Iris Anne, Klepstad, J., Hannezo, E., Lundegaard, Pia Rengtved, Trusina, Ala & Ober, Elke, 2023, In: PLOS Biology. 21, 10, 30 p., e3002315.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development

    sgk681, sgk681, Seymour, Philip Allan, Sneppen, Kim, Trusina, Ala, Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Jensen, Mogens Høgh & Serup, Palle, 2023, In: Nature Communications. 14, 17 p., 348.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2022
  6. Published

    Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming

    Perera Pérez, Marta, Nissen, Silas Boye, Proks, Martin, Pozzi, S., S. Monteiro, Rita, Trusina, Ala & Brickman, Joshua Mark, 15 Aug 2022, In: eLife. 11, 23 p., e78967.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics

    Rothová, M. M., Nielsen, Alexander Valentin, Proks, Martin, Wong, Yan Fung, Riveiro, Alba, Linneberg-Agerholm, Madeleine, David, E., Amit, I., Trusina, Ala & Brickman, Joshua Mark, 2022, In: Nature Cell Biology. 24, 6, p. 833-844 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs

    Son, M., Frank, T., Holst-Hansen, T., Wang, A. G., Junkin, M., Kashaf, S. S., Trusina, Ala & Tay, S., 2 Sep 2022, In: Science Advances. 8, 35, 14 p., 6240.

    Research output: Contribution to journalJournal articlepeer-review

  9. 2021
  10. Published

    Establishment of heterochromatin in domain-size-dependent bursts

    Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.

    Research output: Contribution to journalJournal articlepeer-review

  11. 2020
  12. Published

    Model to Link Cell Shape and Polarity with Organogenesis

    Nielsen, Bjarke Frost, Nissen, Silas Boye, Sneppen, Kim, Mathiesen, Joachim & Trusina, Ala, 10 Jan 2020, In: iScience. 23, 2, p. 1-10 10 p., 100830.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2019
  14. Published

    Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress

    Igbaria, A., Merksamer, P. I., Trusina, Ala, Tilahun, F., Johnson, J. R., Brandman, O., Krogan, N. J., Weissman, J. S. & Papa, F. R., 1 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11291-11298 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Self-assembly, buckling and density-invariant growth of three-dimensional vascular networks

    Kirkegaard, Julius Bier, Nielsen, Bjarke Frost, Trusina, Ala & Sneppen, Kim, 31 Oct 2019, In: Journal of the Royal Society. Interface. 16, 159, 8 p., 20190517.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    The fitness cost and benefit of phase-separated protein deposits

    Sanchez de Groot, N., Torrent Burgas, M., Ravarani, C. N. J., Trusina, Ala, Ventura, S. & Babu, M. M., Apr 2019, In: Molecular Systems Biology. 15, 4, e8075.

    Research output: Contribution to journalJournal articlepeer-review

  17. 2018
  18. Published

    Theoretical tool bridging cell polarities with development of robust morphologies

    Nissen, Silas Boye, Rønhild, S., Trusina, Ala & Sneppen, Kim, 27 Nov 2018, In: eLife. 7, 25 p., e38407.

    Research output: Contribution to journalJournal articlepeer-review

  19. 2017
  20. Published

    Impact of Zygosity on Bimodal Phenotype Distributions

    Holst-Hansen, T., Abad, E., Muntasell, A., López-Botet, M., Jensen, Mogens Høgh, Trusina, Ala & Garcia-Ojalvo, J., 11 Jul 2017, In: Biophysical Journal. 113, 1, p. 148-156 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

    Larsen, Hjalte List, Martin-Coll, L., Nielsen, Alexander Valentin, Wright, C. V. E., Trusina, Ala, Kim, Y. H. & Grapin-Botton, A., 19 Sep 2017, In: Nature Communications. 8, 605.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Four simple rules that are sufficient to generate the mammalian blastocyst

    Nissen, Silas Boye, Perera Pérez, Marta, Martin Gonzalez, Javier, Morgani, S. M. C., Jensen, Mogens Høgh, Sneppen, Kim, Brickman, Joshua Mark & Trusina, Ala, 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.

    Research output: Contribution to journalJournal articlepeer-review

  23. 2016
  24. Published

    Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions

    Di Roberto, R. B., Chang, B., Trusina, Ala & Peisajovich, S. G., 4 Aug 2016, In: Nature Communications. 7, 12344.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Nucleation and spreading of a heterochromatic domain in fission yeast

    Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response

    Vedel, S., Nunns, H., Košmrlj, A., Semsey, S. & Trusina, Ala, 13 Jul 2016, In: Cell Systems. 3, 2, p. 187-198

    Research output: Contribution to journalJournal articlepeer-review

  27. 2014
  28. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Stress induced telomere shortening: longer life with less mutations?

    Trusina, Ala, 1 Mar 2014, In: B M C Systems Biology. 8, 27.

    Research output: Contribution to journalJournal articlepeer-review

  30. 2013
  31. Published

    Noisy transcription factor NF-¿B oscillations stabilize and sensitize cytokine signaling in space

    Gangstad, S. W., Feldager, C. W., Juul, J. S. & Trusina, Ala, 5 Feb 2013, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 87, 2, p. 022702

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Two portable recombination enhancers direct donor choice in fission yeast heterochromatin

    Jakociunas, T., Holm, L. R., Hansen, J. V., Trusina, Ala & Thon, Genevieve, 2013, In: P L o S Genetics. 9, 10, 14 p., e1003762.

    Research output: Contribution to journalJournal articlepeer-review

  33. 2012
  34. Published

    Fragile DNA Repair Mechanism Reduces Ageing in Multicellular Model

    Bendtsen, K. M., Juul, J. S. & Trusina, Ala, 2 May 2012, In: P L o S One. 7, 5, p. e36018

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Conditional Cooperativity in Toxin-Antitoxin Regulation Prevents Random Toxin Activation and Promotes Fast Translational Recovery

    Cataudella, I., Trusina, Ala, Sneppen, Kim, Gerdes, K. & Mitarai, Namiko, 11 Apr 2012, In: Nucleic Acids Research. 40, 14, p. 6424-6434

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    IRE1 alpha Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

    Lerner, A. G., Upton, J., Praveen, P. V. K., Ghosh, R., Nakagawa, Y., Igbaria, A., Shen, S., Nguyen, V., Bradley, B. J., Heiman, M. & Trusina, Ala, 8 Aug 2012, In: Cell Metabolism. 16, 2, p. 250-264 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Circuit architecture explains functional similarity of bacterial heat shock responses

    Masayo, I., Mitarai, Namiko & Trusina, Ala, 1 Dec 2012, In: Physical Biology. 9, 6, p. 066003

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Nested feedback loops in gene regulation

    Mengel, A. B., Krishna, S., Jensen, Mogens Høgh & Trusina, Ala, 1 Jan 2012, In: Physica A: Statistical Mechanics and its Applications. 391, 1-2, p. 100-106

    Research output: Contribution to journalJournal articlepeer-review

  39. 2011
  40. Published

    Targeted bacterial immunity buffres phage diversity

    Härter, Jan Olaf Mirko, Trusina, Ala & Sneppen, Kim, 21 Aug 2011, In: Journal of Virology. 85, 20, p. 10554-10560 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Ecosystems with Mutually Exclusive Interactions Self-Organize to a State of High Diversity

    Mathiesen, Joachim, Mitarai, Namiko, Sneppen, Kim & Trusina, Ala, 25 Oct 2011, In: Physical Review Letters. 107, 18, p. 188101

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Analyzing inflammatory response as excitable media

    Yde, Pernille, Jensen, Mogens Høgh & Trusina, Ala, 18 Nov 2011, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 84, 5, Part 1, p. 051913

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Modeling the NF-kappa B mediated inflammatory response predicts cytokine waves in tissue

    Yde, Pernille, Mengel, A. B., Jensen, Mogens Høgh, Krishna, S. & Trusina, Ala, 19 Jul 2011, In: BMC Systems Biology. 5, p. 115

    Research output: Contribution to journalJournal articlepeer-review

  44. 2010
  45. Published

    Modeling oscillatory control in NF-¿B, p53 and Wnt signaling

    Mengel, B., Hunziker, A., Pedersen, L., Trusina, Ala, Jensen, Mogens Høgh & Krishna, S., 1 Dec 2010, In: Current Opinion in Genetics & Development. 20, 6, p. 656-64 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    A minimal model for multiple epidemics and immunity spreading

    Sneppen, Kim, Trusina, Ala, Jensen, Mogens Høgh & Bornholdt, S., 18 Oct 2010, In: PLoS ONE. 5, 10, p. e13326

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    The unfolded protein response and translation attenuation: a modelling approach.

    Trusina, Ala & Tang, C., Oct 2010, In: Diabetes, Obesity and Metabolism Online. 12, p. 27-31

    Research output: Contribution to journalJournal articlepeer-review

  48. 2009
  49. Published

    Defining Network Topologies that Can Achieve Biochemical Adaptation

    Ma, W., Trusina, Ala, El-Samad, H., Lim, W. A. & Tang, C., 21 Aug 2009, In: Cell. 138, 4, p. 760-773

    Research output: Contribution to journalJournal articlepeer-review

  50. 2008
  51. Published

    Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions

    Merksamer, P., Trusina, Ala & Papa, F., 20 Nov 2008, In: Cell. 135, 5, p. 933-947

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Rationalizing translation attenuation in the network architecture of the unfolded protein response

    Trusina, Ala, Papa, F. R. & Tang, C., 23 Dec 2008, In: Proceedings of the National Academy of Sciences USA (PNAS). 105, 51, p. 20280-20285

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Translation attenuation mechanism in unfolded protein response

    Trusina, Ala, Papa, F. & Tang, C., 1 Dec 2008, Evolution from Cellular to Social Scales. Skjeltorp, A., Skjeltorp, A. & Belushkin, A. (eds.). p. 83-90 8 p. (NATO Science for Peace and Security Series B: Physics and Biophysics).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  54. 2006
  55. Published

    Degree landscapes in scale-free networks

    Axelsen, J. B., Bernhardsson, S., Rosvall, M., Sneppen, Kim & Trusina, Ala, Sep 2006, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 74, 3

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Functional alignment of regulatory networks: a study of temperate phages

    Trusina, Ala, Sneppen, Kim, Dodd, I. B., Shearwin, K. E. & Egan, J. B., 2006, In: PLoS Computational Biology. 1, 7, p. 599-603

    Research output: Contribution to journalJournal articlepeer-review

  57. 2005
  58. Published

    Networks and Cities: An Information Perspective

    Rosvall, M., Trusina, Ala, Minnhagen, P. & Sneppen, Kim, 2005, In: Physical Review Letters. 94, 2, 028701.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Hide-and-seek on complex networks

    Sneppen, Kim, Trusina, Ala & Rosvall, M., Mar 2005, In: EPL. 69, 5, p. 853-859

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Measuring information networks

    Sneppen, Kim, Trusina, Ala & Rosvall, M., Jun 2005, In: Pramana – Journal of Physics. 64, 6, p. 1121-1125

    Research output: Contribution to journalJournal articlepeer-review

  61. 2004
  62. Published

    Self-organization of structures and networks from merging and small-scale fluctuations

    Minnhagen, P., Rosvall, M., Sneppen, Kim & Trusina, Ala, 15 Sep 2004, In: Physica A: Statistical Mechanics and its Applications. 340, 4, p. 725-732

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Hierarchy measures in complex networks

    Trusina, Ala, Maslov, S., Minnhagen, P. & Sneppen, Kim, 30 Apr 2004, In: Physical Review Letters. 92, 17, 178702.

    Research output: Contribution to journalJournal articlepeer-review

  64. 2003
  65. Published

    Prisoners' dilemma in real-world acquaintance networks: Spikes and quasiequilibria induced by the interplay between structure and dynamics

    Holme, P., Trusina, Ala, Kim, B. & Minnhagen, P., Sep 2003, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 68, 3

    Research output: Contribution to journalJournal articlepeer-review

  66. 2002
  67. Published

    Dynamic instabilities induced by asymmetric influence: Prisoners' dilemma game in small-world networks

    Kim, B., Trusina, Ala, Holme, P., Minnhagen, P., Chung, J. & Choi, M., Aug 2002, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 66, 2, 021907.

    Research output: Contribution to journalJournal articlepeer-review

ID: 13307823