Ala Trusina

Ala Trusina

Associate Professor


  1. 2023
  2. Published

    A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation

    Knudsen, Teresa Emmilie Toudal, Hamilton, W. B., Proks, Martin, Lykkegaard, M., Linneberg-Agerholm, Madeleine, Nielsen, Alexander Valentin, Perera Pérez, Marta, Malzard, L. L., Trusina, Ala & Brickman, Joshua Mark, 2023, In: Cell Systems. 14, 9, p. 788-805.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development

    sgk681, sgk681, Seymour, Philip Allan, Sneppen, Kim, Trusina, Ala, Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Jensen, Mogens Høgh & Serup, Palle, 2023, In: Nature Communications. 14, 17 p., 348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

    Unterweger, Iris Anne, Klepstad, J., Hannezo, E., Lundegaard, Pia Rengtved, Trusina, Ala & Ober, Elke, 2023, In: PLOS Biology. 21, 10, 30 p., e3002315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2022
  6. Published

    Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs

    Son, M., Frank, T., Holst-Hansen, T., Wang, A. G., Junkin, M., Kashaf, S. S., Trusina, Ala & Tay, S., 2 Sep 2022, In: Science Advances. 8, 35, 14 p., 6240.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming

    Perera Pérez, Marta, Nissen, Silas Boye, Proks, Martin, Pozzi, S., S. Monteiro, Rita, Trusina, Ala & Brickman, Joshua Mark, 15 Aug 2022, In: eLife. 11, 23 p., e78967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics

    Rothová, M. M., Nielsen, Alexander Valentin, Proks, Martin, Wong, Yan Fung, Riveiro, Alba, Linneberg-Agerholm, Madeleine, David, E., Amit, I., Trusina, Ala & Brickman, Joshua Mark, 2022, In: Nature Cell Biology. 24, 6, p. 833-844 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2021
  10. Published

    Establishment of heterochromatin in domain-size-dependent bursts

    Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2020
  12. Published

    Model to Link Cell Shape and Polarity with Organogenesis

    Nielsen, Bjarke Frost, Nissen, Silas Boye, Sneppen, Kim, Mathiesen, Joachim & Trusina, Ala, 10 Jan 2020, In: iScience. 23, 2, p. 1-10 10 p., 100830.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2019
  14. Published

    Self-assembly, buckling and density-invariant growth of three-dimensional vascular networks

    Kirkegaard, Julius Bier, Nielsen, Bjarke Frost, Trusina, Ala & Sneppen, Kim, 31 Oct 2019, In: Journal of the Royal Society. Interface. 16, 159, 8 p., 20190517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The fitness cost and benefit of phase-separated protein deposits

    Sanchez de Groot, N., Torrent Burgas, M., Ravarani, C. N. J., Trusina, Ala, Ventura, S. & Babu, M. M., Apr 2019, In: Molecular Systems Biology. 15, 4, e8075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress

    Igbaria, A., Merksamer, P. I., Trusina, Ala, Tilahun, F., Johnson, J. R., Brandman, O., Krogan, N. J., Weissman, J. S. & Papa, F. R., 1 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11291-11298 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    Theoretical tool bridging cell polarities with development of robust morphologies

    Nissen, Silas Boye, Rønhild, S., Trusina, Ala & Sneppen, Kim, 27 Nov 2018, In: eLife. 7, 25 p., e38407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2017
  20. Published

    Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

    Larsen, Hjalte List, Martin-Coll, L., Nielsen, Alexander Valentin, Wright, C. V. E., Trusina, Ala, Kim, Y. H. & Grapin-Botton, A., 19 Sep 2017, In: Nature Communications. 8, 605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Four simple rules that are sufficient to generate the mammalian blastocyst

    Nissen, Silas Boye, Perera Pérez, Marta, Martin Gonzalez, Javier, Morgani, S. M. C., Jensen, Mogens Høgh, Sneppen, Kim, Brickman, Joshua Mark & Trusina, Ala, 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Impact of Zygosity on Bimodal Phenotype Distributions

    Holst-Hansen, T., Abad, E., Muntasell, A., López-Botet, M., Jensen, Mogens Høgh, Trusina, Ala & Garcia-Ojalvo, J., 11 Jul 2017, In: Biophysical Journal. 113, 1, p. 148-156 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2016
  24. Published

    Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions

    Di Roberto, R. B., Chang, B., Trusina, Ala & Peisajovich, S. G., 4 Aug 2016, In: Nature Communications. 7, 12344.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response

    Vedel, S., Nunns, H., Košmrlj, A., Semsey, S. & Trusina, Ala, 13 Jul 2016, In: Cell Systems. 3, 2, p. 187-198

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Nucleation and spreading of a heterochromatic domain in fission yeast

    Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2014
  28. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Stress induced telomere shortening: longer life with less mutations?

    Trusina, Ala, 1 Mar 2014, In: B M C Systems Biology. 8, 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2013
  31. Published

    Noisy transcription factor NF-¿B oscillations stabilize and sensitize cytokine signaling in space

    Gangstad, S. W., Feldager, C. W., Juul, J. S. & Trusina, Ala, 5 Feb 2013, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 87, 2, p. 022702

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Two portable recombination enhancers direct donor choice in fission yeast heterochromatin

    Jakociunas, T., Holm, L. R., Hansen, J. V., Trusina, Ala & Thon, Genevieve, 2013, In: P L o S Genetics. 9, 10, 14 p., e1003762.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2012
  34. Published

    Circuit architecture explains functional similarity of bacterial heat shock responses

    Masayo, I., Mitarai, Namiko & Trusina, Ala, 1 Dec 2012, In: Physical Biology. 9, 6, p. 066003

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    IRE1 alpha Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

    Lerner, A. G., Upton, J., Praveen, P. V. K., Ghosh, R., Nakagawa, Y., Igbaria, A., Shen, S., Nguyen, V., Bradley, B. J., Heiman, M. & Trusina, Ala, 8 Aug 2012, In: Cell Metabolism. 16, 2, p. 250-264 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Fragile DNA Repair Mechanism Reduces Ageing in Multicellular Model

    Bendtsen, K. M., Juul, J. S. & Trusina, Ala, 2 May 2012, In: P L o S One. 7, 5, p. e36018

    Research output: Contribution to journalJournal articleResearchpeer-review

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