Activity pulses induce spontaneous flow reversals in viscoelastic environments

Research output: Contribution to journalJournal articlepeer-review

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Activity pulses induce spontaneous flow reversals in viscoelastic environments. / Plan, Emmanuel L. C. V. I. M.; Yeomans, Julia M.; Doostmohammadi, Amin.

In: Interface Focus, Vol. 18, No. 177, 20210100, 14.04.2021.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Plan, ELCVIM, Yeomans, JM & Doostmohammadi, A 2021, 'Activity pulses induce spontaneous flow reversals in viscoelastic environments', Interface Focus, vol. 18, no. 177, 20210100. https://doi.org/10.1098/rsif.2021.0100

APA

Plan, E. L. C. V. I. M., Yeomans, J. M., & Doostmohammadi, A. (2021). Activity pulses induce spontaneous flow reversals in viscoelastic environments. Interface Focus, 18(177), [20210100]. https://doi.org/10.1098/rsif.2021.0100

Vancouver

Plan ELCVIM, Yeomans JM, Doostmohammadi A. Activity pulses induce spontaneous flow reversals in viscoelastic environments. Interface Focus. 2021 Apr 14;18(177). 20210100. https://doi.org/10.1098/rsif.2021.0100

Author

Plan, Emmanuel L. C. V. I. M. ; Yeomans, Julia M. ; Doostmohammadi, Amin. / Activity pulses induce spontaneous flow reversals in viscoelastic environments. In: Interface Focus. 2021 ; Vol. 18, No. 177.

Bibtex

@article{73321f14d1af4b6b9c37904880df7353,
title = "Activity pulses induce spontaneous flow reversals in viscoelastic environments",
abstract = "Complex interactions between cellular systems and their surrounding extracellular matrices are emerging as important mechanical regulators of cell functions, such as proliferation, motility and cell death, and such cellular systems are often characterized by pulsating actomyosin activities. Here, using an active gel model, we numerically explore spontaneous flow generation by activity pulses in the presence of a viscoelastic medium. The results show that cross-talk between the activity-induced deformations of the viscoelastic surroundings and the time-dependent response of the active medium to these deformations can lead to the reversal of spontaneously generated active flows. We explain the mechanism behind this phenomenon based on the interaction between the active flow and the viscoelastic medium. We show the importance of relaxation time scales of both the polymers and the active particles and provide a phase space over which such spontaneous flow reversals can be observed. Our results suggest new experiments investigating the role of controlled pulses of activity in living systems ensnared in complex mircoenvironments.",
keywords = "flow reversal, active matter, viscoelastic effects, activity pulse, polymer relaxation",
author = "Plan, {Emmanuel L. C. V. I. M.} and Yeomans, {Julia M.} and Amin Doostmohammadi",
year = "2021",
month = apr,
day = "14",
doi = "10.1098/rsif.2021.0100",
language = "English",
volume = "18",
journal = "Journal of the Royal Society Interface",
issn = "2042-8898",
publisher = "Royal Society, The",
number = "177",

}

RIS

TY - JOUR

T1 - Activity pulses induce spontaneous flow reversals in viscoelastic environments

AU - Plan, Emmanuel L. C. V. I. M.

AU - Yeomans, Julia M.

AU - Doostmohammadi, Amin

PY - 2021/4/14

Y1 - 2021/4/14

N2 - Complex interactions between cellular systems and their surrounding extracellular matrices are emerging as important mechanical regulators of cell functions, such as proliferation, motility and cell death, and such cellular systems are often characterized by pulsating actomyosin activities. Here, using an active gel model, we numerically explore spontaneous flow generation by activity pulses in the presence of a viscoelastic medium. The results show that cross-talk between the activity-induced deformations of the viscoelastic surroundings and the time-dependent response of the active medium to these deformations can lead to the reversal of spontaneously generated active flows. We explain the mechanism behind this phenomenon based on the interaction between the active flow and the viscoelastic medium. We show the importance of relaxation time scales of both the polymers and the active particles and provide a phase space over which such spontaneous flow reversals can be observed. Our results suggest new experiments investigating the role of controlled pulses of activity in living systems ensnared in complex mircoenvironments.

AB - Complex interactions between cellular systems and their surrounding extracellular matrices are emerging as important mechanical regulators of cell functions, such as proliferation, motility and cell death, and such cellular systems are often characterized by pulsating actomyosin activities. Here, using an active gel model, we numerically explore spontaneous flow generation by activity pulses in the presence of a viscoelastic medium. The results show that cross-talk between the activity-induced deformations of the viscoelastic surroundings and the time-dependent response of the active medium to these deformations can lead to the reversal of spontaneously generated active flows. We explain the mechanism behind this phenomenon based on the interaction between the active flow and the viscoelastic medium. We show the importance of relaxation time scales of both the polymers and the active particles and provide a phase space over which such spontaneous flow reversals can be observed. Our results suggest new experiments investigating the role of controlled pulses of activity in living systems ensnared in complex mircoenvironments.

KW - flow reversal

KW - active matter

KW - viscoelastic effects

KW - activity pulse

KW - polymer relaxation

U2 - 10.1098/rsif.2021.0100

DO - 10.1098/rsif.2021.0100

M3 - Journal article

C2 - 33849330

VL - 18

JO - Journal of the Royal Society Interface

JF - Journal of the Royal Society Interface

SN - 2042-8898

IS - 177

M1 - 20210100

ER -

ID: 261608479