Activity-induced instabilities of brain organoids

Research output: Contribution to journalJournal articlepeer-review

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Activity-induced instabilities of brain organoids. / Thijssen, Kristian; Kusters, Guido L. A.; Doostmohammadi, Amin.

In: The European Physical Journal E: Soft Matter and Biological Physics, Vol. 44, No. 12, 147, 07.12.2021.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Thijssen, K, Kusters, GLA & Doostmohammadi, A 2021, 'Activity-induced instabilities of brain organoids', The European Physical Journal E: Soft Matter and Biological Physics, vol. 44, no. 12, 147. https://doi.org/10.1140/epje/s10189-021-00149-z

APA

Thijssen, K., Kusters, G. L. A., & Doostmohammadi, A. (2021). Activity-induced instabilities of brain organoids. The European Physical Journal E: Soft Matter and Biological Physics, 44(12), [147]. https://doi.org/10.1140/epje/s10189-021-00149-z

Vancouver

Thijssen K, Kusters GLA, Doostmohammadi A. Activity-induced instabilities of brain organoids. The European Physical Journal E: Soft Matter and Biological Physics. 2021 Dec 7;44(12). 147. https://doi.org/10.1140/epje/s10189-021-00149-z

Author

Thijssen, Kristian ; Kusters, Guido L. A. ; Doostmohammadi, Amin. / Activity-induced instabilities of brain organoids. In: The European Physical Journal E: Soft Matter and Biological Physics. 2021 ; Vol. 44, No. 12.

Bibtex

@article{50df49a7675f464097510a2252e479e7,
title = "Activity-induced instabilities of brain organoids",
abstract = "We present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to explain the experimental observation of surface instabilities in brain organoids, the role of activity has been largely overlooked. Our results show that the active stress generated by the cells can be a, previously overlooked, contributor to the emergence of surface deformations in brain organoids.",
keywords = "REVEAL, GELS",
author = "Kristian Thijssen and Kusters, {Guido L. A.} and Amin Doostmohammadi",
year = "2021",
month = dec,
day = "7",
doi = "10.1140/epje/s10189-021-00149-z",
language = "English",
volume = "44",
journal = "European Physical Journal E",
issn = "1292-8941",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Activity-induced instabilities of brain organoids

AU - Thijssen, Kristian

AU - Kusters, Guido L. A.

AU - Doostmohammadi, Amin

PY - 2021/12/7

Y1 - 2021/12/7

N2 - We present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to explain the experimental observation of surface instabilities in brain organoids, the role of activity has been largely overlooked. Our results show that the active stress generated by the cells can be a, previously overlooked, contributor to the emergence of surface deformations in brain organoids.

AB - We present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to explain the experimental observation of surface instabilities in brain organoids, the role of activity has been largely overlooked. Our results show that the active stress generated by the cells can be a, previously overlooked, contributor to the emergence of surface deformations in brain organoids.

KW - REVEAL

KW - GELS

U2 - 10.1140/epje/s10189-021-00149-z

DO - 10.1140/epje/s10189-021-00149-z

M3 - Journal article

C2 - 34874504

VL - 44

JO - European Physical Journal E

JF - European Physical Journal E

SN - 1292-8941

IS - 12

M1 - 147

ER -

ID: 286991680