Synthesis of long T silicon nanoparticles for hyperpolarized Si magnetic resonance imaging

Research output: Contribution to journalJournal articlepeer-review

We describe the synthesis, materials characterization, and dynamic nuclear polarization (DNP) of amorphous and crystalline silicon nanoparticles for use as hyperpolarized magnetic resonance imaging (MRI) agents. The particles were synthesized by means of a metathesis reaction between sodium silicide (Na Si) and silicon tetrachloride (SiCl) and were surface functionalized with a variety of passivating ligands. The synthesis scheme results in particles of diameter ~10 nm with long size-adjusted Si spin-lattice relaxation (T) times (>600 s), which are retained after hyperpolarization by low-temperature DNP.
Original languageEnglish
JournalA C S Nano
Volume7
Issue number2
Pages (from-to)1609-1617
Number of pages9
ISSN1936-0851
DOIs
Publication statusPublished - 26 Feb 2013

ID: 45588431