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Edgar Villagran-Vargas*, and Vladimir Serkin
Universidad De La Salle, Bajio Campestre, Mexico.


Title: The Nonlinear Schrödinger Equation for the Description of Mechanical Changes in Phase with the Action Potential in Neurons

Abstract: In this work we show that, using the reductive perturbation method, an action potential, considered as a carrier wave modulation propagating in a neuronal axon, may be described by the Nonlinear Schrödinger Equation (NLS). ÊBy modeling the neuronal axon as a fluid-filled elastic tube composed of elastic rings we also propose that the localized pressure increase in the fluid (Soliton) causes a radially symmetric expansion of the elastic rings in the region of the pressure increase, which is consistent with the experimental observations carried out quite recently by Gonzalez et al., (submitted 2016), who found that mechanical changes in the axon membrane i.e. a swelling of a few nm occur in phase with the action potentials. The novel soliton solutions of the NLS model are being explored in order to describe phenomena occurring in neurons such as pulse attraction-repulsion recently observed (Villagran et al., 2013). We also discuss the possibility to apply this model to neural networks in order to describe both the probability of pulse transmission to the postsynaptic neuron and the Êaction potential back-propagation.

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