Clustering on Membranes: Fluctuations and More

Research output: Contribution to journal › Review › Research › peer-review

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Clustering on Membranes : Fluctuations and More. / Johannes, Ludger; Pezeshkian, Weria; Ipsen, John H.; Shillcock, Julian C.

In: Trends in Cell Biology, Vol. 28, No. 5, 05.2018, p. 405-415.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Johannes, L, Pezeshkian, W, Ipsen, JH & Shillcock, JC 2018, 'Clustering on Membranes: Fluctuations and More', Trends in Cell Biology, vol. 28, no. 5, pp. 405-415. https://doi.org/10.1016/j.tcb.2018.01.009

APA

Johannes, L., Pezeshkian, W., Ipsen, J. H., & Shillcock, J. C. (2018). Clustering on Membranes: Fluctuations and More. Trends in Cell Biology, 28(5), 405-415. https://doi.org/10.1016/j.tcb.2018.01.009

Vancouver

Johannes L, Pezeshkian W, Ipsen JH, Shillcock JC. Clustering on Membranes: Fluctuations and More. Trends in Cell Biology. 2018 May;28(5):405-415. https://doi.org/10.1016/j.tcb.2018.01.009

Author

Johannes, Ludger ; Pezeshkian, Weria ; Ipsen, John H. ; Shillcock, Julian C. / Clustering on Membranes : Fluctuations and More. In: Trends in Cell Biology. 2018 ; Vol. 28, No. 5. pp. 405-415.

Bibtex

@article{f110f0493b5d4a3b97943ce607e49734,
title = "Clustering on Membranes: Fluctuations and More",
abstract = "Clustering of extracellular ligands and proteins on the plasma membrane is required to perform specific cellular functions, such as signaling and endocytosis. Attractive forces that originate in perturbations of the membrane's physical properties contribute to this clustering, in addition to direct protein-protein interactions. However, these membrane-mediated forces have not all been equally considered, despite their importance. In this review, we describe how line tension, lipid depletion, and membrane curvature contribute to membrane-mediated clustering. Additional attractive forces that arise from protein-induced perturbation of a membrane's fluctuations are also described. This review aims to provide a survey of the current understanding of membrane-mediated clustering and how this supports precise biological functions.",
keywords = "CURVATURE-MEDIATED INTERACTIONS, CELL-MEMBRANE, PLASMA-MEMBRANES, BIOLOGICAL-MEMBRANES, ANCHORED PROTEINS, PHASE-SEPARATION, LIPID-BILAYERS, INDUCED FORCES, ORGANIZATION, RAFTS",
author = "Ludger Johannes and Weria Pezeshkian and Ipsen, {John H.} and Shillcock, {Julian C.}",
year = "2018",
month = may,
doi = "10.1016/j.tcb.2018.01.009",
language = "English",
volume = "28",
pages = "405--415",
journal = "Trends in Cell Biology",
issn = "0962-8924",
publisher = "Elsevier Ltd. * Trends Journals",
number = "5",

}

RIS

TY - JOUR

T1 - Clustering on Membranes

T2 - Fluctuations and More

AU - Johannes, Ludger

AU - Pezeshkian, Weria

AU - Ipsen, John H.

AU - Shillcock, Julian C.

PY - 2018/5

Y1 - 2018/5

N2 - Clustering of extracellular ligands and proteins on the plasma membrane is required to perform specific cellular functions, such as signaling and endocytosis. Attractive forces that originate in perturbations of the membrane's physical properties contribute to this clustering, in addition to direct protein-protein interactions. However, these membrane-mediated forces have not all been equally considered, despite their importance. In this review, we describe how line tension, lipid depletion, and membrane curvature contribute to membrane-mediated clustering. Additional attractive forces that arise from protein-induced perturbation of a membrane's fluctuations are also described. This review aims to provide a survey of the current understanding of membrane-mediated clustering and how this supports precise biological functions.

AB - Clustering of extracellular ligands and proteins on the plasma membrane is required to perform specific cellular functions, such as signaling and endocytosis. Attractive forces that originate in perturbations of the membrane's physical properties contribute to this clustering, in addition to direct protein-protein interactions. However, these membrane-mediated forces have not all been equally considered, despite their importance. In this review, we describe how line tension, lipid depletion, and membrane curvature contribute to membrane-mediated clustering. Additional attractive forces that arise from protein-induced perturbation of a membrane's fluctuations are also described. This review aims to provide a survey of the current understanding of membrane-mediated clustering and how this supports precise biological functions.

KW - CURVATURE-MEDIATED INTERACTIONS

KW - CELL-MEMBRANE

KW - PLASMA-MEMBRANES

KW - BIOLOGICAL-MEMBRANES

KW - ANCHORED PROTEINS

KW - PHASE-SEPARATION

KW - LIPID-BILAYERS

KW - INDUCED FORCES

KW - ORGANIZATION

KW - RAFTS

U2 - 10.1016/j.tcb.2018.01.009

DO - 10.1016/j.tcb.2018.01.009

M3 - Review

VL - 28

SP - 405

EP - 415

JO - Trends in Cell Biology

JF - Trends in Cell Biology

SN - 0962-8924

IS - 5

ER -

ID: 316865659