Harnessing precursor-directed biosynthesis with glucose derivatives to access cotton fibers with enhanced physical properties
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Harnessing precursor-directed biosynthesis with glucose derivatives to access cotton fibers with enhanced physical properties. / Kuperman, Ofir Aharon; de Andrade, Peterson; Sui, Xiao Meng; Maria, Raquel; Kaplan-Ashiri, Ifat; Jiang, Qixiang; Terlier, Tanguy; Kirkensgaard, Jacob Judas Kain; Field, Robert A.; Natalio, Filipe.
In: Cell Reports Physical Science, Vol. 5, No. 5, 101963, 2024.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Harnessing precursor-directed biosynthesis with glucose derivatives to access cotton fibers with enhanced physical properties
AU - Kuperman, Ofir Aharon
AU - de Andrade, Peterson
AU - Sui, Xiao Meng
AU - Maria, Raquel
AU - Kaplan-Ashiri, Ifat
AU - Jiang, Qixiang
AU - Terlier, Tanguy
AU - Kirkensgaard, Jacob Judas Kain
AU - Field, Robert A.
AU - Natalio, Filipe
N1 - Publisher Copyright: © 2024 The Author(s)
PY - 2024
Y1 - 2024
N2 - Cotton ovule in vitro cultures are a promising platform for exploring biofabrication of fibers with tailored properties. When the ovules' growth medium is supplemented with chemically synthesized cellulose precursors, it results in their integration into the developing fibers, thereby tailoring their end properties. Here, we report the feeding of synthetic glucosyl phosphate derivative, 6-deoxy-6-fluoro-glucose-1-phosphate (6F-Glc-1P) to cotton ovules growing in vitro, demonstrating the metabolic incorporation of 6F-Glc into the fibers with enhanced mechanical properties and moisture-retention capacity while emphasizing the role of molecular hierarchical architecture in defining functional characteristics and mechanical properties. This incorporation strategy bypasses the early steps of conventional metabolic pathways while broadening the range of functionalities that can be employed to customize fiber end properties. Our approach combines materials science, chemistry, and plant sciences to illustrate the innovation required to find alternative solutions for sustainable production of functional cotton fibers with enhanced and emergent properties.
AB - Cotton ovule in vitro cultures are a promising platform for exploring biofabrication of fibers with tailored properties. When the ovules' growth medium is supplemented with chemically synthesized cellulose precursors, it results in their integration into the developing fibers, thereby tailoring their end properties. Here, we report the feeding of synthetic glucosyl phosphate derivative, 6-deoxy-6-fluoro-glucose-1-phosphate (6F-Glc-1P) to cotton ovules growing in vitro, demonstrating the metabolic incorporation of 6F-Glc into the fibers with enhanced mechanical properties and moisture-retention capacity while emphasizing the role of molecular hierarchical architecture in defining functional characteristics and mechanical properties. This incorporation strategy bypasses the early steps of conventional metabolic pathways while broadening the range of functionalities that can be employed to customize fiber end properties. Our approach combines materials science, chemistry, and plant sciences to illustrate the innovation required to find alternative solutions for sustainable production of functional cotton fibers with enhanced and emergent properties.
KW - cotton fibers
KW - metabolic incorporation
KW - modified properties
KW - synthetic glucose derivatives
U2 - 10.1016/j.xcrp.2024.101963
DO - 10.1016/j.xcrp.2024.101963
M3 - Journal article
AN - SCOPUS:85192964299
VL - 5
JO - Cell Reports Physical Science
JF - Cell Reports Physical Science
SN - 2666-3864
IS - 5
M1 - 101963
ER -
ID: 392715888