Nanocarriers of antigen proteins for vaccine delivery

Research output: Contribution to journal › Review › Research › peer-review

Standard

Nanocarriers of antigen proteins for vaccine delivery. / Lopes Chaves, Luíse; Dourado, Douglas; Prunache, Ioana-Bianca; Manuelle Marques da Silva, Paloma; Tacyana Dos Santos Lucena, Gislayne; Cardoso de Souza, Zilyane; Muniz Mendes Freire de Moura, Patrícia; Nunes Bordallo, Heloísa; Rocha Formiga, Fabio; de Souza Rebouças, Juliana.

In: International Journal of Pharmaceutics, Vol. 659, 124162, 25.06.2024.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Lopes Chaves, L, Dourado, D, Prunache, I-B, Manuelle Marques da Silva, P, Tacyana Dos Santos Lucena, G, Cardoso de Souza, Z, Muniz Mendes Freire de Moura, P, Nunes Bordallo, H, Rocha Formiga, F & de Souza Rebouças, J 2024, 'Nanocarriers of antigen proteins for vaccine delivery', International Journal of Pharmaceutics, vol. 659, 124162. https://doi.org/10.1016/j.ijpharm.2024.124162

APA

Lopes Chaves, L., Dourado, D., Prunache, I-B., Manuelle Marques da Silva, P., Tacyana Dos Santos Lucena, G., Cardoso de Souza, Z., Muniz Mendes Freire de Moura, P., Nunes Bordallo, H., Rocha Formiga, F., & de Souza Rebouças, J. (2024). Nanocarriers of antigen proteins for vaccine delivery. International Journal of Pharmaceutics, 659, [124162]. https://doi.org/10.1016/j.ijpharm.2024.124162

Vancouver

Lopes Chaves L, Dourado D, Prunache I-B, Manuelle Marques da Silva P, Tacyana Dos Santos Lucena G, Cardoso de Souza Z et al. Nanocarriers of antigen proteins for vaccine delivery. International Journal of Pharmaceutics. 2024 Jun 25;659. 124162. https://doi.org/10.1016/j.ijpharm.2024.124162

Author

Lopes Chaves, Luíse ; Dourado, Douglas ; Prunache, Ioana-Bianca ; Manuelle Marques da Silva, Paloma ; Tacyana Dos Santos Lucena, Gislayne ; Cardoso de Souza, Zilyane ; Muniz Mendes Freire de Moura, Patrícia ; Nunes Bordallo, Heloísa ; Rocha Formiga, Fabio ; de Souza Rebouças, Juliana. / Nanocarriers of antigen proteins for vaccine delivery. In: International Journal of Pharmaceutics. 2024 ; Vol. 659.

Bibtex

@article{9fb5fbe616444b67b10e1fca89f67b02,

title = "Nanocarriers of antigen proteins for vaccine delivery",

abstract = "Nanoformulations in vaccinology provide antigen stability and enhanced immunogenicity, in addition to providing targeted delivery and controlled release. In the last years, much research has been focused on vaccine development using virus-like particles, liposomes, emulsions, polymeric, lipid, and inorganic nanoparticles. Importantly, nanoparticle interactions with innate and adaptive immune systems must be clearly understood to guide the rational development of nanovaccines. This review provides a recap and updates on different aspects advocating nanoparticles as promising antigen carriers and immune cell activators for vaccination. Moreover, it offers a discussion of how the physicochemical properties of nanoparticles are modified to target specific cells and improve vaccine efficacy.",

keywords = "Humans, Vaccines/administration & dosage, Animals, Nanoparticles, Antigens/administration & dosage, Drug Carriers/chemistry, Drug Delivery Systems/methods, Nanoparticle Drug Delivery System/chemistry",

author = "{Lopes Chaves}, Lu{\'i}se and Douglas Dourado and Ioana-Bianca Prunache and {Manuelle Marques da Silva}, Paloma and {Tacyana Dos Santos Lucena}, Gislayne and {Cardoso de Souza}, Zilyane and {Muniz Mendes Freire de Moura}, Patr{\'i}cia and {Nunes Bordallo}, Helo{\'i}sa and {Rocha Formiga}, Fabio and {de Souza Rebou{\c c}as}, Juliana",

note = "Copyright {\textcopyright} 2024. Published by Elsevier B.V.",

year = "2024",

month = jun,

day = "25",

doi = "10.1016/j.ijpharm.2024.124162",

language = "English",

volume = "659",

journal = "International Journal of Pharmaceutics",

issn = "0378-5173",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Nanocarriers of antigen proteins for vaccine delivery

AU - Lopes Chaves, Luíse

AU - Dourado, Douglas

AU - Prunache, Ioana-Bianca

AU - Manuelle Marques da Silva, Paloma

AU - Tacyana Dos Santos Lucena, Gislayne

AU - Cardoso de Souza, Zilyane

AU - Muniz Mendes Freire de Moura, Patrícia

AU - Nunes Bordallo, Heloísa

AU - Rocha Formiga, Fabio

AU - de Souza Rebouças, Juliana

PY - 2024/6/25

Y1 - 2024/6/25

N2 - Nanoformulations in vaccinology provide antigen stability and enhanced immunogenicity, in addition to providing targeted delivery and controlled release. In the last years, much research has been focused on vaccine development using virus-like particles, liposomes, emulsions, polymeric, lipid, and inorganic nanoparticles. Importantly, nanoparticle interactions with innate and adaptive immune systems must be clearly understood to guide the rational development of nanovaccines. This review provides a recap and updates on different aspects advocating nanoparticles as promising antigen carriers and immune cell activators for vaccination. Moreover, it offers a discussion of how the physicochemical properties of nanoparticles are modified to target specific cells and improve vaccine efficacy.

AB - Nanoformulations in vaccinology provide antigen stability and enhanced immunogenicity, in addition to providing targeted delivery and controlled release. In the last years, much research has been focused on vaccine development using virus-like particles, liposomes, emulsions, polymeric, lipid, and inorganic nanoparticles. Importantly, nanoparticle interactions with innate and adaptive immune systems must be clearly understood to guide the rational development of nanovaccines. This review provides a recap and updates on different aspects advocating nanoparticles as promising antigen carriers and immune cell activators for vaccination. Moreover, it offers a discussion of how the physicochemical properties of nanoparticles are modified to target specific cells and improve vaccine efficacy.

KW - Humans

KW - Vaccines/administration & dosage

KW - Animals

KW - Nanoparticles

KW - Antigens/administration & dosage

KW - Drug Carriers/chemistry

KW - Drug Delivery Systems/methods

KW - Nanoparticle Drug Delivery System/chemistry

U2 - 10.1016/j.ijpharm.2024.124162

DO - 10.1016/j.ijpharm.2024.124162

M3 - Review

C2 - 38663646

VL - 659

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

SN - 0378-5173

M1 - 124162

ER -

ID: 397936116