Progressive practice promotes motor learning and repeated transient increases in corticospinal excitability across multiple days
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Progressive practice promotes motor learning and repeated transient increases in corticospinal excitability across multiple days. / Christiansen, Lasse; Madsen, Mads Alexander Just; Bojsen-Møller, Emil; Thomas, Richard; Nielsen, Jens Bo; Lundbye-Jensen, Jesper.
In: Brain Stimulation, Vol. 11, No. 2, 2018, p. 346-357.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Progressive practice promotes motor learning and repeated transient increases in corticospinal excitability across multiple days
AU - Christiansen, Lasse
AU - Madsen, Mads Alexander Just
AU - Bojsen-Møller, Emil
AU - Thomas, Richard
AU - Nielsen, Jens Bo
AU - Lundbye-Jensen, Jesper
N1 - CURIS 2018 NEXS 048
PY - 2018
Y1 - 2018
N2 - Background: A session of motor skill learning is accompanied by transient increases in corticospinal excitability (CSE), which are thought to reflect acute changes in neuronal connectivity associated with improvements in sensorimotor performance. Factors influencing changes in excitability and motor skillwith continued practice remain however to be elucidated.Objective/Hypothesis: Here we investigate the hypothesis that progressive motor practice during consecutive days can induce repeated transient increases in corticospinal excitability and promote motor skill learning.Methods: Changes in motor performance and CSE were assessed during 4 consecutive days of skill learning and 8 days after the last practice session. CSE was assessed as area under recruitment curves (RC) using transcranial magnetic stimulation (TMS). Two groups of participants (n = 12) practiced a visuomotortracking-task with task difficulty progressively increased with individual proficiency (PPG) or with the same task level throughout all 4 days (NPPG).Results: Progressive practice resulted in superior motor learning compared to NPPG (p < 0.001). Whereas NPPG displayed increased CSE following only the first day of practice (p < 0.001), progressive motor practice was accompanied by increases in CSE on both the first and the final session of motor practice (p = 0.006). Eight days after ended practice, the groups showed similar CSE, but PPG maintained superior performance at a skilled task level and transfer task performance (p < 0.005, p = 0.029).Conclusion: The results demonstrate that progressive practice promotes both motor learning and repeated increases in CSE across multiple days. While changes in CSE did not relate to learning our results suggest that they signify successful training. Progressive practice is thus important for optimizingneurorehabilitation and motor practice protocols in general.
AB - Background: A session of motor skill learning is accompanied by transient increases in corticospinal excitability (CSE), which are thought to reflect acute changes in neuronal connectivity associated with improvements in sensorimotor performance. Factors influencing changes in excitability and motor skillwith continued practice remain however to be elucidated.Objective/Hypothesis: Here we investigate the hypothesis that progressive motor practice during consecutive days can induce repeated transient increases in corticospinal excitability and promote motor skill learning.Methods: Changes in motor performance and CSE were assessed during 4 consecutive days of skill learning and 8 days after the last practice session. CSE was assessed as area under recruitment curves (RC) using transcranial magnetic stimulation (TMS). Two groups of participants (n = 12) practiced a visuomotortracking-task with task difficulty progressively increased with individual proficiency (PPG) or with the same task level throughout all 4 days (NPPG).Results: Progressive practice resulted in superior motor learning compared to NPPG (p < 0.001). Whereas NPPG displayed increased CSE following only the first day of practice (p < 0.001), progressive motor practice was accompanied by increases in CSE on both the first and the final session of motor practice (p = 0.006). Eight days after ended practice, the groups showed similar CSE, but PPG maintained superior performance at a skilled task level and transfer task performance (p < 0.005, p = 0.029).Conclusion: The results demonstrate that progressive practice promotes both motor learning and repeated increases in CSE across multiple days. While changes in CSE did not relate to learning our results suggest that they signify successful training. Progressive practice is thus important for optimizingneurorehabilitation and motor practice protocols in general.
KW - Faculty of Science
KW - TMS
KW - Learning
KW - Plasticity
KW - Corticospinal excitability
U2 - 10.1016/j.brs.2017.11.005
DO - 10.1016/j.brs.2017.11.005
M3 - Journal article
C2 - 29187320
VL - 11
SP - 346
EP - 357
JO - Brain Stimulation
JF - Brain Stimulation
SN - 1935-861X
IS - 2
ER -
ID: 185841440