Application of enriched stable isotopes as tracers in biological systems: a critical review
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Application of enriched stable isotopes as tracers in biological systems : a critical review. / Stürup, Stefan; Hansen, Helle Rüsz; Gammelgaard, Bente.
I: Analytical and Bioanalytical Chemistry, Bind 390, Nr. 2, 2008, s. 541-554.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Application of enriched stable isotopes as tracers in biological systems
T2 - a critical review
AU - Stürup, Stefan
AU - Hansen, Helle Rüsz
AU - Gammelgaard, Bente
PY - 2008
Y1 - 2008
N2 - The application of enriched stable isotopes of minerals and trace elements as tracers in biological systems is a rapidly growing research field that benefits from the many new developments in inorganic mass spectrometric instrumentation, primarily within inductively coupled plasma mass spectrometry (ICP-MS) instrumentation, such as reaction/collision cell ICP-MS and multicollector ICP-MS with improved isotope ratio measurement and interference removal capabilities. Adaptation and refinement of radioisotope tracer experiment methodologies for enriched stable isotope experiments, and the development of new methodologies coupled with more advanced compartmental and mathematical models for the distribution of elements in living organisms has enabled a broader use of enriched stable isotope experiments in the biological sciences. This review discusses the current and future uses of enriched stable isotope experiments in biological systems.
AB - The application of enriched stable isotopes of minerals and trace elements as tracers in biological systems is a rapidly growing research field that benefits from the many new developments in inorganic mass spectrometric instrumentation, primarily within inductively coupled plasma mass spectrometry (ICP-MS) instrumentation, such as reaction/collision cell ICP-MS and multicollector ICP-MS with improved isotope ratio measurement and interference removal capabilities. Adaptation and refinement of radioisotope tracer experiment methodologies for enriched stable isotope experiments, and the development of new methodologies coupled with more advanced compartmental and mathematical models for the distribution of elements in living organisms has enabled a broader use of enriched stable isotope experiments in the biological sciences. This review discusses the current and future uses of enriched stable isotope experiments in biological systems.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1007/s00216-007-1638-8
DO - 10.1007/s00216-007-1638-8
M3 - Review
C2 - 17917720
VL - 390
SP - 541
EP - 554
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
SN - 1618-2642
IS - 2
ER -
ID: 2998393