Peptoid-Peptide hybrid backbone architectures
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Peptidomimetic oligomers and foldamers have received considerable attention for over a decade, with beta-peptides and the so-called peptoids (N-alkylglycine oligomers) representing prominent examples of such architectures. Lately, hybrid or mixed backbones consisting of both alpha- and beta-amino acids (alpha/beta-peptides) have been investigated in some detail as well. The present Minireview is a survey of the literature concerning hybrid structures of alpha-amino acids and peptoids, including beta-peptoids (N-alkyl-beta-alanine oligomers), and is intended to give an overview of this area of research within the field of peptidomimetic science.
Originalsprog | Engelsk |
---|---|
Tidsskrift | ChemBioChem |
Vol/bind | 11 |
Udgave nummer | 2 |
Sider (fra-til) | 152-160 |
ISSN | 1439-4227 |
DOI | |
Status | Udgivet - 25 jan. 2010 |
Bibliografisk note
Keywords: foldamers, hybrid backbones, medicinal chemistry, peptidomimetics, peptoids
- Det tidligere Farmaceutiske Fakultet
Forskningsområder
ID: 33701810