Ala Trusina
Associate Professor
Biocomplexity
Blegdamsvej 17
2100 København Ø
- Published
Model to Link Cell Shape and Polarity with Organogenesis
Nielsen, Bjarke Frost, Nissen, Silas Boye, Sneppen, Kim, Mathiesen, Joachim & Trusina, Ala, 10 Jan 2020, In: iScience. 23, 2, p. 1-10 10 p., 100830.Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling oscillatory control in NF-¿B, p53 and Wnt signaling
Mengel, B., Hunziker, A., Pedersen, L., Trusina, Ala, Jensen, Mogens Høgh & Krishna, S., 1 Dec 2010, In: Current Opinion in Genetics & Development. 20, 6, p. 656-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analyzing inflammatory response as excitable media
Yde, Pernille, Jensen, Mogens Høgh & Trusina, Ala, 18 Nov 2011, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 84, 5, Part 1, p. 051913Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragile DNA Repair Mechanism Reduces Ageing in Multicellular Model
Bendtsen, K. M., Juul, J. S. & Trusina, Ala, 2 May 2012, In: P L o S One. 7, 5, p. e36018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response
Vedel, S., Nunns, H., Košmrlj, A., Semsey, S. & Trusina, Ala, 13 Jul 2016, In: Cell Systems. 3, 2, p. 187-198Research output: Contribution to journal › Journal article › Research › peer-review
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Hide-and-seek on complex networks
Sneppen, Kim, Trusina, Ala & Rosvall, M., Mar 2005, In: EPL. 69, 5, p. 853-859Research output: Contribution to journal › Journal article › Research › peer-review
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Prisoners' dilemma in real-world acquaintance networks: Spikes and quasiequilibria induced by the interplay between structure and dynamics
Holme, P., Trusina, Ala, Kim, B. & Minnhagen, P., Sep 2003, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 68, 3Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli
Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516Research output: Contribution to journal › Journal article › Research › peer-review
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A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation
Knudsen, Teresa Emmilie Toudal, Hamilton, W. B., Proks, Martin, Lykkegaard, M., Linneberg-Agerholm, M., Nielsen, Alexander Valentin, Perera Pérez, Marta, Malzard, L. L., Trusina, Ala & Brickman, Joshua Mark, 2023, In: Cell Systems. 14, 9, p. 788-805.e8Research output: Contribution to journal › Journal article › Research › peer-review
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Synergistic and antagonistic effects of deterministic and stochastic cell-cell variations
Vedel, S., Košmrlj, A., Nunns, H. & Trusina, Ala, 9 May 2024, In: Physical Review E. 109, 5, 17 p., 054404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The fitness cost and benefit of phase-separated protein deposits
Sanchez de Groot, N., Torrent Burgas, M., Ravarani, C. N. J., Trusina, Ala, Ventura, S. & Babu, M. M., Apr 2019, In: Molecular Systems Biology. 15, 4, e8075.Research output: Contribution to journal › Journal article › Research › peer-review
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Self-assembly, buckling and density-invariant growth of three-dimensional vascular networks
Kirkegaard, Julius Bier, Nielsen, Bjarke Frost, Trusina, Ala & Sneppen, Kim, 31 Oct 2019, In: Journal of the Royal Society. Interface. 16, 159, 8 p., 20190517.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ecosystems with Mutually Exclusive Interactions Self-Organize to a State of High Diversity
Mathiesen, Joachim, Mitarai, Namiko, Sneppen, Kim & Trusina, Ala, 25 Oct 2011, In: Physical Review Letters. 107, 18, p. 188101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted bacterial immunity buffres phage diversity
Härter, Jan Olaf Mirko, Trusina, Ala & Sneppen, Kim, 21 Aug 2011, In: Journal of Virology. 85, 20, p. 10554-10560 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circuit architecture explains functional similarity of bacterial heat shock responses
Masayo, I., Mitarai, Namiko & Trusina, Ala, 1 Dec 2012, In: Physical Biology. 9, 6, p. 066003Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defining Network Topologies that Can Achieve Biochemical Adaptation
Ma, W., Trusina, Ala, El-Samad, H., Lim, W. A. & Tang, C., 21 Aug 2009, In: Cell. 138, 4, p. 760-773Research output: Contribution to journal › Journal article › Research › peer-review
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Self-organization of structures and networks from merging and small-scale fluctuations
Minnhagen, P., Rosvall, M., Sneppen, Kim & Trusina, Ala, 15 Sep 2004, In: Physica A: Statistical Mechanics and its Applications. 340, 4, p. 725-732Research output: Contribution to journal › Journal article › Research › peer-review
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Establishment of heterochromatin in domain-size-dependent bursts
Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.Research output: Contribution to journal › Journal article › Research › peer-review
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Stress induced telomere shortening: longer life with less mutations?
Trusina, Ala, 1 Mar 2014, In: B M C Systems Biology. 8, 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling the NF-kappa B mediated inflammatory response predicts cytokine waves in tissue
Yde, Pernille, Mengel, A. B., Jensen, Mogens Høgh, Krishna, S. & Trusina, Ala, 19 Jul 2011, In: BMC Systems Biology. 5, p. 115Research output: Contribution to journal › Journal article › Research › peer-review
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Noisy transcription factor NF-¿B oscillations stabilize and sensitize cytokine signaling in space
Gangstad, S. W., Feldager, C. W., Juul, J. S. & Trusina, Ala, 5 Feb 2013, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 87, 2, p. 022702Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions
Di Roberto, R. B., Chang, B., Trusina, Ala & Peisajovich, S. G., 4 Aug 2016, In: Nature Communications. 7, 12344.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic instabilities induced by asymmetric influence: Prisoners' dilemma game in small-world networks
Kim, B., Trusina, Ala, Holme, P., Minnhagen, P., Chung, J. & Choi, M., Aug 2002, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 66, 2, 021907.Research output: Contribution to journal › Journal article › Research › peer-review
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Degree landscapes in scale-free networks
Axelsen, J. B., Bernhardsson, S., Rosvall, M., Sneppen, Kim & Trusina, Ala, Sep 2006, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 74, 3Research output: Contribution to journal › Journal article › Research › peer-review
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Four simple rules that are sufficient to generate the mammalian blastocyst
Nissen, Silas Boye, Perera Pérez, Marta, Martin Gonzalez, Javier, Morgani, S. M. C., Jensen, Mogens Høgh, Sneppen, Kim, Brickman, Joshua Mark & Trusina, Ala, 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics
Unterweger, Iris Anne, Klepstad, J., Hannezo, E., Lundegaard, Pia Rengtved, Trusina, Ala & Ober, Elke, 2023, In: PLOS Biology. 21, 10, 30 p., e3002315.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs
Son, M., Frank, T., Holst-Hansen, T., Wang, A. G., Junkin, M., Kashaf, S. S., Trusina, Ala & Tay, S., 2 Sep 2022, In: Science Advances. 8, 35, 14 p., 6240.Research output: Contribution to journal › Journal article › Research › peer-review
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Networks and Cities: An Information Perspective
Rosvall, M., Trusina, Ala, Minnhagen, P. & Sneppen, Kim, 2005, In: Physical Review Letters. 94, 2, 028701.Research output: Contribution to journal › Journal article › Research › peer-review
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A minimal model for multiple epidemics and immunity spreading
Sneppen, Kim, Trusina, Ala, Jensen, Mogens Høgh & Bornholdt, S., 18 Oct 2010, In: PLoS ONE. 5, 10, p. e13326Research output: Contribution to journal › Journal article › Research › peer-review
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Two portable recombination enhancers direct donor choice in fission yeast heterochromatin
Jakociunas, T., Holm, L. R., Hansen, J. V., Trusina, Ala & Thon, Genevieve, 2013, In: P L o S Genetics. 9, 10, 14 p., e1003762.Research output: Contribution to journal › Journal article › Research › peer-review
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Hierarchy measures in complex networks
Trusina, Ala, Maslov, S., Minnhagen, P. & Sneppen, Kim, 30 Apr 2004, In: Physical Review Letters. 92, 17, 178702.Research output: Contribution to journal › Journal article › Research › peer-review
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Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development
sgk681, sgk681, Seymour, Philip Allan, Sneppen, Kim, Trusina, Ala, Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Jensen, Mogens Høgh & Serup, Palle, 2023, In: Nature Communications. 14, 17 p., 348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress
Igbaria, A., Merksamer, P. I., Trusina, Ala, Tilahun, F., Johnson, J. R., Brandman, O., Krogan, N. J., Weissman, J. S. & Papa, F. R., 1 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11291-11298 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional alignment of regulatory networks: a study of temperate phages
Trusina, Ala, Sneppen, Kim, Dodd, I. B., Shearwin, K. E. & Egan, J. B., 2006, In: PLoS Computational Biology. 1, 7, p. 599-603Research output: Contribution to journal › Journal article › Research › peer-review
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IRE1 alpha Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress
Lerner, A. G., Upton, J., Praveen, P. V. K., Ghosh, R., Nakagawa, Y., Igbaria, A., Shen, S., Nguyen, V., Bradley, B. J., Heiman, M. & Trusina, Ala, 8 Aug 2012, In: Cell Metabolism. 16, 2, p. 250-264 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions
Merksamer, P., Trusina, Ala & Papa, F., 20 Nov 2008, In: Cell. 135, 5, p. 933-947Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring information networks
Sneppen, Kim, Trusina, Ala & Rosvall, M., Jun 2005, In: Pramana – Journal of Physics. 64, 6, p. 1121-1125Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rationalizing translation attenuation in the network architecture of the unfolded protein response
Trusina, Ala, Papa, F. R. & Tang, C., 23 Dec 2008, In: Proceedings of the National Academy of Sciences USA (PNAS). 105, 51, p. 20280-20285Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis
Larsen, Hjalte List, Martin-Coll, L., Nielsen, Alexander Valentin, Wright, C. V. E., Trusina, Ala, Kim, Y. H. & Grapin-Botton, A., 19 Sep 2017, In: Nature Communications. 8, 605.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming
Perera Pérez, Marta, Nissen, Silas Boye, Proks, Martin, Pozzi, S., S. Monteiro, Rita, Trusina, Ala & Brickman, Joshua Mark, 15 Aug 2022, In: eLife. 11, 23 p., e78967.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conditional Cooperativity in Toxin-Antitoxin Regulation Prevents Random Toxin Activation and Promotes Fast Translational Recovery
Cataudella, I., Trusina, Ala, Sneppen, Kim, Gerdes, K. & Mitarai, Namiko, 11 Apr 2012, In: Nucleic Acids Research. 40, 14, p. 6424-6434Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Theoretical tool bridging cell polarities with development of robust morphologies
Nissen, Silas Boye, Rønhild, S., Trusina, Ala & Sneppen, Kim, 27 Nov 2018, In: eLife. 7, 25 p., e38407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Zygosity on Bimodal Phenotype Distributions
Holst-Hansen, T., Abad, E., Muntasell, A., López-Botet, M., Jensen, Mogens Høgh, Trusina, Ala & Garcia-Ojalvo, J., 11 Jul 2017, In: Biophysical Journal. 113, 1, p. 148-156 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics
Rothová, M. M., Nielsen, Alexander Valentin, Proks, Martin, Wong, Yan Fung, Riveiro, A. R., Linneberg-Agerholm, M., David, E., Amit, I., Trusina, Ala & Brickman, Joshua Mark, 2022, In: Nature Cell Biology. 24, 6, p. 833-844 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translation attenuation mechanism in unfolded protein response
Trusina, Ala, Papa, F. & Tang, C., 1 Dec 2008, Evolution from Cellular to Social Scales. Skjeltorp, A., Skjeltorp, A. & Belushkin, A. (eds.). p. 83-90 8 p. (NATO Science for Peace and Security Series B: Physics and Biophysics).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Nested feedback loops in gene regulation
Mengel, A. B., Krishna, S., Jensen, Mogens Høgh & Trusina, Ala, 1 Jan 2012, In: Physica A: Statistical Mechanics and its Applications. 391, 1-2, p. 100-106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nucleation and spreading of a heterochromatic domain in fission yeast
Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.Research output: Contribution to journal › Journal article › Research › peer-review
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The unfolded protein response and translation attenuation: a modelling approach.
Trusina, Ala & Tang, C., Oct 2010, In: Diabetes, Obesity and Metabolism Online. 12, p. 27-31Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13307823
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Two portable recombination enhancers direct donor choice in fission yeast heterochromatin
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1029
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Modeling the NF-kappa B mediated inflammatory response predicts cytokine waves in tissue
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
901
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A minimal model for multiple epidemics and immunity spreading
Research output: Contribution to journal › Journal article › Research › peer-review
Published