Peptoid-Peptide hybrid backbone architectures
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Peptoid-Peptide hybrid backbone architectures. / Olsen, Christian Adam.
I: ChemBioChem, Bind 11, Nr. 2, 25.01.2010, s. 152-160.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Peptoid-Peptide hybrid backbone architectures
AU - Olsen, Christian Adam
N1 - Keywords: foldamers, hybrid backbones, medicinal chemistry, peptidomimetics, peptoids
PY - 2010/1/25
Y1 - 2010/1/25
N2 - Peptidomimetic oligomers and foldamers have received considerable attention for over a decade, with beta-peptides and the so-called peptoids (N-alkylglycine oligomers) representing prominent examples of such architectures. Lately, hybrid or mixed backbones consisting of both alpha- and beta-amino acids (alpha/beta-peptides) have been investigated in some detail as well. The present Minireview is a survey of the literature concerning hybrid structures of alpha-amino acids and peptoids, including beta-peptoids (N-alkyl-beta-alanine oligomers), and is intended to give an overview of this area of research within the field of peptidomimetic science.
AB - Peptidomimetic oligomers and foldamers have received considerable attention for over a decade, with beta-peptides and the so-called peptoids (N-alkylglycine oligomers) representing prominent examples of such architectures. Lately, hybrid or mixed backbones consisting of both alpha- and beta-amino acids (alpha/beta-peptides) have been investigated in some detail as well. The present Minireview is a survey of the literature concerning hybrid structures of alpha-amino acids and peptoids, including beta-peptoids (N-alkyl-beta-alanine oligomers), and is intended to give an overview of this area of research within the field of peptidomimetic science.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1002/cbic.200900618
DO - 10.1002/cbic.200900618
M3 - Journal article
C2 - 20017179
VL - 11
SP - 152
EP - 160
JO - ChemBioChem
JF - ChemBioChem
SN - 1439-4227
IS - 2
ER -
ID: 33701810