Programming strategy for efficient modeling of dynamics in a population of heterogeneous cells
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Programming strategy for efficient modeling of dynamics in a population of heterogeneous cells. / Hald, Bjørn Olav; Hendriksen, Morten; Sørensen, Preben Graae.
I: Bioinformatics, Bind 29, Nr. 10, 2013, s. 1292-1298.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Programming strategy for efficient modeling of dynamics in a population of heterogeneous cells
AU - Hald, Bjørn Olav
AU - Hendriksen, Morten
AU - Sørensen, Preben Graae
PY - 2013
Y1 - 2013
N2 - Heterogeneity is a ubiquitous property of biological systems. Even in a genetically identical population of a single cell type, cell-to-cell differences are observed. Although the functional behavior of a given population is generally robust, the consequences of heterogeneity are fairly unpredictable. In heterogeneous populations, synchronization of events becomes a cardinal problem-particularly for phase coherence in oscillating systems.
AB - Heterogeneity is a ubiquitous property of biological systems. Even in a genetically identical population of a single cell type, cell-to-cell differences are observed. Although the functional behavior of a given population is generally robust, the consequences of heterogeneity are fairly unpredictable. In heterogeneous populations, synchronization of events becomes a cardinal problem-particularly for phase coherence in oscillating systems.
KW - Faculty of Health and Medical Sciences
U2 - 10.1093/bioinformatics/btt132
DO - 10.1093/bioinformatics/btt132
M3 - Journal article
C2 - 23505296
VL - 29
SP - 1292
EP - 1298
JO - Computer Applications in the Biosciences
JF - Computer Applications in the Biosciences
SN - 1471-2105
IS - 10
ER -
ID: 45812968