The effect of stretching on nerve excitability
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The effect of stretching on nerve excitability. / Heimburg, Thomas.
I: Human Movement Science, Bind 86, 103000, 07.10.2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The effect of stretching on nerve excitability
AU - Heimburg, Thomas
PY - 2022/10/7
Y1 - 2022/10/7
N2 - Nerves are frequently stretched during movement. We investigate here the effect of stretch on nerve excitability within the framework of the soliton theory. This thermodynamic theory for nerve pulse propagation relies on the presence of a melting transition in the nerve membrane. In this transition, the area of the nerve membrane and the nerve thickness change. It depends on thermodynamic variables including temperature, the chemical potentials of anesthetics and on hydrostatic pressure. A further variable relevant for movement science is the the stretching of nerves, i.e., a tension in the nerve caused by muscle contraction, the bending of joints and the pulling on extremities. We show here that the soliton theory predicts a decrease in nerve excit-ability upon stretching. This becomes evident in a reduction of the amplitude of compound action potentials and in the suppression of reflexes. We compare these predictions with medical findings.
AB - Nerves are frequently stretched during movement. We investigate here the effect of stretch on nerve excitability within the framework of the soliton theory. This thermodynamic theory for nerve pulse propagation relies on the presence of a melting transition in the nerve membrane. In this transition, the area of the nerve membrane and the nerve thickness change. It depends on thermodynamic variables including temperature, the chemical potentials of anesthetics and on hydrostatic pressure. A further variable relevant for movement science is the the stretching of nerves, i.e., a tension in the nerve caused by muscle contraction, the bending of joints and the pulling on extremities. We show here that the soliton theory predicts a decrease in nerve excit-ability upon stretching. This becomes evident in a reduction of the amplitude of compound action potentials and in the suppression of reflexes. We compare these predictions with medical findings.
KW - Stretching
KW - Reflexes
KW - Solitons
KW - MECHANICAL CHANGES
KW - LIPID-MEMBRANES
KW - IN-VITRO
KW - STIMULATION
KW - CONDUCTION
KW - FIBERS
KW - NEUROMODULATION
KW - THERMODYNAMICS
KW - CATIONS
U2 - 10.1016/j.humov.2022.103000
DO - 10.1016/j.humov.2022.103000
M3 - Journal article
C2 - 36209614
VL - 86
JO - Human Movement Science
JF - Human Movement Science
SN - 0167-9457
M1 - 103000
ER -
ID: 324368155