Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study

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Standard

Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles : A Synchrotron Small-Angle X-ray Scattering (SAXS) Study. / Ghazal, Aghiad; Gontsarik, Mark; Kutter, Jörg P.; Lafleur, Josiane P.; Ahmadvand, Davoud; Labrador, Ana; Salentinig, Stefan; Yaghmur, Anan.

I: The Journal of Physical Chemistry Letters, Bind 17, 2017, s. 73-79.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Ghazal, A, Gontsarik, M, Kutter, JP, Lafleur, JP, Ahmadvand, D, Labrador, A, Salentinig, S & Yaghmur, A 2017, 'Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study', The Journal of Physical Chemistry Letters, bind 17, s. 73-79. https://doi.org/10.1021/acs.jpclett.6b02468

APA

Ghazal, A., Gontsarik, M., Kutter, J. P., Lafleur, J. P., Ahmadvand, D., Labrador, A., Salentinig, S., & Yaghmur, A. (2017). Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study. The Journal of Physical Chemistry Letters, 17, 73-79. https://doi.org/10.1021/acs.jpclett.6b02468

Vancouver

Ghazal A, Gontsarik M, Kutter JP, Lafleur JP, Ahmadvand D, Labrador A o.a. Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study. The Journal of Physical Chemistry Letters. 2017;17:73-79. https://doi.org/10.1021/acs.jpclett.6b02468

Author

Ghazal, Aghiad ; Gontsarik, Mark ; Kutter, Jörg P. ; Lafleur, Josiane P. ; Ahmadvand, Davoud ; Labrador, Ana ; Salentinig, Stefan ; Yaghmur, Anan. / Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles : A Synchrotron Small-Angle X-ray Scattering (SAXS) Study. I: The Journal of Physical Chemistry Letters. 2017 ; Bind 17. s. 73-79.

Bibtex

@article{d43d74b7d36540ff8257b09b8084dfc2,
title = "Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study",
abstract = "A microfluidic platform combined with synchrotron small-angle X-ray scattering (SAXS) was used for monitoring the continuous production of multilamellar vesicles (MLVs). Their production was fast and started to evolve within less than 0.43 s of contact between the lipids and the aqueous phase. To obtain nanoparticles with a narrow size distribution, it was important to use a modified hydrodynamic flow focusing (HFF) microfluidic device with narrower microchannels than those normally used for SAXS experiments. Monodispersed MLVs as small as 160 nm in size, with a polydispersity index (PDI) of approximately 0.15 were achieved. The nanoparticles produced were smaller and had a narrower size distribution than those obtained via conventional bulk mixing methods. This microfluidic platform therefore has a great potential for the continuous production of monodispersed NPs.",
author = "Aghiad Ghazal and Mark Gontsarik and Kutter, {J{\"o}rg P.} and Lafleur, {Josiane P.} and Davoud Ahmadvand and Ana Labrador and Stefan Salentinig and Anan Yaghmur",
year = "2017",
doi = "10.1021/acs.jpclett.6b02468",
language = "English",
volume = "17",
pages = "73--79",
journal = "Journal of Physical Chemistry Letters",
issn = "1948-7185",
publisher = "American Chemical Society",

}

RIS

TY - JOUR

T1 - Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles

T2 - A Synchrotron Small-Angle X-ray Scattering (SAXS) Study

AU - Ghazal, Aghiad

AU - Gontsarik, Mark

AU - Kutter, Jörg P.

AU - Lafleur, Josiane P.

AU - Ahmadvand, Davoud

AU - Labrador, Ana

AU - Salentinig, Stefan

AU - Yaghmur, Anan

PY - 2017

Y1 - 2017

N2 - A microfluidic platform combined with synchrotron small-angle X-ray scattering (SAXS) was used for monitoring the continuous production of multilamellar vesicles (MLVs). Their production was fast and started to evolve within less than 0.43 s of contact between the lipids and the aqueous phase. To obtain nanoparticles with a narrow size distribution, it was important to use a modified hydrodynamic flow focusing (HFF) microfluidic device with narrower microchannels than those normally used for SAXS experiments. Monodispersed MLVs as small as 160 nm in size, with a polydispersity index (PDI) of approximately 0.15 were achieved. The nanoparticles produced were smaller and had a narrower size distribution than those obtained via conventional bulk mixing methods. This microfluidic platform therefore has a great potential for the continuous production of monodispersed NPs.

AB - A microfluidic platform combined with synchrotron small-angle X-ray scattering (SAXS) was used for monitoring the continuous production of multilamellar vesicles (MLVs). Their production was fast and started to evolve within less than 0.43 s of contact between the lipids and the aqueous phase. To obtain nanoparticles with a narrow size distribution, it was important to use a modified hydrodynamic flow focusing (HFF) microfluidic device with narrower microchannels than those normally used for SAXS experiments. Monodispersed MLVs as small as 160 nm in size, with a polydispersity index (PDI) of approximately 0.15 were achieved. The nanoparticles produced were smaller and had a narrower size distribution than those obtained via conventional bulk mixing methods. This microfluidic platform therefore has a great potential for the continuous production of monodispersed NPs.

U2 - 10.1021/acs.jpclett.6b02468

DO - 10.1021/acs.jpclett.6b02468

M3 - Journal article

C2 - 27936765

VL - 17

SP - 73

EP - 79

JO - Journal of Physical Chemistry Letters

JF - Journal of Physical Chemistry Letters

SN - 1948-7185

ER -

ID: 170018396