Small-angle scattering studies of intrinsically disordered proteins and their complexes

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Small-angle scattering studies of intrinsically disordered proteins and their complexes. / Cordeiro, Tiago N.; Herranz-Trillo, Fátima; Urbanek, Annika; Estaña, Alejandro; Cortés, Juan; Sibille, Nathalie; Bernadó, Pau.

I: Current Opinion in Structural Biology, Bind 42, 2017, s. 15-23.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Cordeiro, TN, Herranz-Trillo, F, Urbanek, A, Estaña, A, Cortés, J, Sibille, N & Bernadó, P 2017, 'Small-angle scattering studies of intrinsically disordered proteins and their complexes', Current Opinion in Structural Biology, bind 42, s. 15-23. https://doi.org/10.1016/j.sbi.2016.10.011

APA

Cordeiro, T. N., Herranz-Trillo, F., Urbanek, A., Estaña, A., Cortés, J., Sibille, N., & Bernadó, P. (2017). Small-angle scattering studies of intrinsically disordered proteins and their complexes. Current Opinion in Structural Biology, 42, 15-23. https://doi.org/10.1016/j.sbi.2016.10.011

Vancouver

Cordeiro TN, Herranz-Trillo F, Urbanek A, Estaña A, Cortés J, Sibille N o.a. Small-angle scattering studies of intrinsically disordered proteins and their complexes. Current Opinion in Structural Biology. 2017;42:15-23. https://doi.org/10.1016/j.sbi.2016.10.011

Author

Cordeiro, Tiago N. ; Herranz-Trillo, Fátima ; Urbanek, Annika ; Estaña, Alejandro ; Cortés, Juan ; Sibille, Nathalie ; Bernadó, Pau. / Small-angle scattering studies of intrinsically disordered proteins and their complexes. I: Current Opinion in Structural Biology. 2017 ; Bind 42. s. 15-23.

Bibtex

@article{a37488da68b34970bf3730657bafee3f,
title = "Small-angle scattering studies of intrinsically disordered proteins and their complexes",
abstract = "Intrinsically Disordered Proteins (IDPs) perform a broad range of biological functions. Their relevance has motivated intense research activity seeking to characterize their sequence/structure/function relationships. However, the conformational plasticity of these molecules hampers the application of traditional structural approaches, and new tools and concepts are being developed to address the challenges they pose. Small-Angle Scattering (SAS) is a structural biology technique that probes the size and shape of disordered proteins and their complexes with other biomolecules. The low-resolution nature of SAS can be compensated with specially designed computational tools and its combined interpretation with complementary structural information. In this review, we describe recent advances in the application of SAS to disordered proteins and highly flexible complexes and discuss current challenges.",
author = "Cordeiro, {Tiago N.} and F{\'a}tima Herranz-Trillo and Annika Urbanek and Alejandro Esta{\~n}a and Juan Cort{\'e}s and Nathalie Sibille and Pau Bernad{\'o}",
year = "2017",
doi = "10.1016/j.sbi.2016.10.011",
language = "English",
volume = "42",
pages = "15--23",
journal = "Current Opinion in Structural Biology",
issn = "0959-440X",
publisher = "Elsevier Ltd. * Current Opinion Journals",

}

RIS

TY - JOUR

T1 - Small-angle scattering studies of intrinsically disordered proteins and their complexes

AU - Cordeiro, Tiago N.

AU - Herranz-Trillo, Fátima

AU - Urbanek, Annika

AU - Estaña, Alejandro

AU - Cortés, Juan

AU - Sibille, Nathalie

AU - Bernadó, Pau

PY - 2017

Y1 - 2017

N2 - Intrinsically Disordered Proteins (IDPs) perform a broad range of biological functions. Their relevance has motivated intense research activity seeking to characterize their sequence/structure/function relationships. However, the conformational plasticity of these molecules hampers the application of traditional structural approaches, and new tools and concepts are being developed to address the challenges they pose. Small-Angle Scattering (SAS) is a structural biology technique that probes the size and shape of disordered proteins and their complexes with other biomolecules. The low-resolution nature of SAS can be compensated with specially designed computational tools and its combined interpretation with complementary structural information. In this review, we describe recent advances in the application of SAS to disordered proteins and highly flexible complexes and discuss current challenges.

AB - Intrinsically Disordered Proteins (IDPs) perform a broad range of biological functions. Their relevance has motivated intense research activity seeking to characterize their sequence/structure/function relationships. However, the conformational plasticity of these molecules hampers the application of traditional structural approaches, and new tools and concepts are being developed to address the challenges they pose. Small-Angle Scattering (SAS) is a structural biology technique that probes the size and shape of disordered proteins and their complexes with other biomolecules. The low-resolution nature of SAS can be compensated with specially designed computational tools and its combined interpretation with complementary structural information. In this review, we describe recent advances in the application of SAS to disordered proteins and highly flexible complexes and discuss current challenges.

U2 - 10.1016/j.sbi.2016.10.011

DO - 10.1016/j.sbi.2016.10.011

M3 - Review

C2 - 27794210

AN - SCOPUS:84992597889

VL - 42

SP - 15

EP - 23

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

SN - 0959-440X

ER -

ID: 196140637