Fertilizer type affects stable isotope ratios of nitrogen in human blood plasma - results from two-year controlled agricultural field trials and a randomized crossover dietary intervention study
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Dokumenter
- Mie et al_Agricultural and Food Chemistry_2022_Vol 70(11)_3391-3399
Forlagets udgivne version, 1,33 MB, PDF-dokument
The stable nitrogen isotope ratio δ15N is used as a marker of dietary protein sources in blood. Crop fertilization strategies affect δ15N in plant foods. In a double-blinded randomized cross-over dietary intervention trial with 33 participants, we quantified the effect of fertilizer type (conventional: synthetic fertilizer and organic: animal or green manure) on δ15N in blood plasma. At study baseline, plasma δ15N was +9.34 ± 0.29‰ (mean ± standard deviation). After 12 days intervention with a diet based on crops fertilized with animal manure, plasma δ15N was shifted by +0.27 ± 0.04‰ (mean ± standard error) compared to synthetic fertilization and by +0.22 ± 0.04‰ compared to fertilization with green manure (both p < 0.0001). Accordingly, differences in the δ15N values between fertilizers are propagated to the blood plasma of human consumers. The results indicate a need to consider agricultural practices when using δ15N as a dietary biomarker.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Agricultural and Food Chemistry |
Vol/bind | 70 |
Udgave nummer | 11 |
Sider (fra-til) | 3391-3399 |
Antal sider | 9 |
ISSN | 0021-8561 |
DOI | |
Status | Udgivet - 2022 |
Bibliografisk note
CURIS 2022 NEXS 079
- Det Natur- og Biovidenskabelige Fakultet
Forskningsområder
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