Glucose transporter 1 localisation throughout pregnancy in the carnivore placenta: light and electron microscope studies
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Glucose transporter 1 localisation throughout pregnancy in the carnivore placenta : light and electron microscope studies. / Wooding, F.B.P.; Dantzer, Vibeke; Klisch, K.; Jones, C.J.; Forhead, A.J.
I: Placenta, Bind 28, Nr. 5-6, 2007, s. 453-464.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Glucose transporter 1 localisation throughout pregnancy in the carnivore placenta
T2 - light and electron microscope studies
AU - Wooding, F.B.P.
AU - Dantzer, Vibeke
AU - Klisch, K.
AU - Jones, C.J.
AU - Forhead, A.J.
PY - 2007
Y1 - 2007
N2 - Glucose is one of the major fetal nutrients. Maternofetal transfer requires transport across the several placental membranes. This transfer is mediated by one or more of the fourteen known isoforms of glucose transporter. So far only Glucose Transporters 1 and 3 (GT1, GT3) have been shown to be located in placental membranes. GT1 may be the only one on the syncytiotrophoblast (human) or both may be present on the same membrane (rodents) or be required in sequence (ruminants, horses and elephant). This paper shows GT1 to be the only transporter demonstrable by immunocytochemistry in carnivore (cat, dog and mink) endotheliochorial placental membranes. GT1 is invariably present on both apical and basal surfaces of the cyto- and syncytiotrophoblast in all carnivore species examined and the pattern of development is described from implantation to term.
AB - Glucose is one of the major fetal nutrients. Maternofetal transfer requires transport across the several placental membranes. This transfer is mediated by one or more of the fourteen known isoforms of glucose transporter. So far only Glucose Transporters 1 and 3 (GT1, GT3) have been shown to be located in placental membranes. GT1 may be the only one on the syncytiotrophoblast (human) or both may be present on the same membrane (rodents) or be required in sequence (ruminants, horses and elephant). This paper shows GT1 to be the only transporter demonstrable by immunocytochemistry in carnivore (cat, dog and mink) endotheliochorial placental membranes. GT1 is invariably present on both apical and basal surfaces of the cyto- and syncytiotrophoblast in all carnivore species examined and the pattern of development is described from implantation to term.
KW - Former LIFE faculty
KW - Glucose transporters
KW - Placenta
KW - Immunocytochemistry
KW - Electron microscopy
KW - Carnivore
U2 - 10.1016/j.placenta.2006.07.006
DO - 10.1016/j.placenta.2006.07.006
M3 - Journal article
C2 - 17027079
VL - 28
SP - 453
EP - 464
JO - Placenta
JF - Placenta
SN - 0143-4004
IS - 5-6
ER -
ID: 8069354