Nutritional management of diabetes mellitus during the pandemic of COVID-19: a comprehensive narrative review
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Nutritional management of diabetes mellitus during the pandemic of COVID-19: a comprehensive narrative review. / Mahluji, Sepideh; Jalili, Mahsa; Ostadrahimi, Alireza; Hallajzadeh, Jamal; Ebrahimzadeh Attari, Vahideh; Saghafi Asl, Maryam.
I: Journal of Diabetes and Metabolic Disorders, Bind 20, Nr. 1, 2021, s. 963-972.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Nutritional management of diabetes mellitus during the pandemic of COVID-19: a comprehensive narrative review
AU - Mahluji, Sepideh
AU - Jalili, Mahsa
AU - Ostadrahimi, Alireza
AU - Hallajzadeh, Jamal
AU - Ebrahimzadeh Attari, Vahideh
AU - Saghafi Asl, Maryam
N1 - (Ekstern)
PY - 2021
Y1 - 2021
N2 - Objectives: According to the recent epidemiological studies, patients with diabetes mellitus (DM) may be at higher risk of hospitalization due to COVID-19. Regarding the important role of nutrition on the immunity, the present review article aimed to outline nutritional support of DM during the outbreak of COVID-19 with a mechanistic insight.Methods: Searches were performed in PubMed/MEDLINE, ScienceDirect, Scopus, and Google Scholar databases from 2000 until December 2020 using the following keywords. All relevant clinical and experimental studies published in English were included.Results: Evidences revealed that hyperglycemia is a significant predictor of some viral infections including COVID-19 which can exacerbate the complications of DM. According to the literature review, adequate intake of dietary protein, fiber, essential fatty acids and some micronutrients especially vitamins D, C, B12, folate, zinc and selenium has beneficial effects on the prevention and treatment of COVID-19 in diabetic patients through modulation of innate and adaptive immune responses or direct effects on virus enzymes or the rate of cell entrance.Conclusions: It is well understood that malnutrition may increase susceptibility to viral infections and disease progression. Therefore, considering nutritional status of diabetic patients and reasonable supplementation of the above mentioned nutrients can ameliorate the symptoms of COVID-19 in DM. However, further well-designed clinical trials are needed to determine their therapeutic dose.
AB - Objectives: According to the recent epidemiological studies, patients with diabetes mellitus (DM) may be at higher risk of hospitalization due to COVID-19. Regarding the important role of nutrition on the immunity, the present review article aimed to outline nutritional support of DM during the outbreak of COVID-19 with a mechanistic insight.Methods: Searches were performed in PubMed/MEDLINE, ScienceDirect, Scopus, and Google Scholar databases from 2000 until December 2020 using the following keywords. All relevant clinical and experimental studies published in English were included.Results: Evidences revealed that hyperglycemia is a significant predictor of some viral infections including COVID-19 which can exacerbate the complications of DM. According to the literature review, adequate intake of dietary protein, fiber, essential fatty acids and some micronutrients especially vitamins D, C, B12, folate, zinc and selenium has beneficial effects on the prevention and treatment of COVID-19 in diabetic patients through modulation of innate and adaptive immune responses or direct effects on virus enzymes or the rate of cell entrance.Conclusions: It is well understood that malnutrition may increase susceptibility to viral infections and disease progression. Therefore, considering nutritional status of diabetic patients and reasonable supplementation of the above mentioned nutrients can ameliorate the symptoms of COVID-19 in DM. However, further well-designed clinical trials are needed to determine their therapeutic dose.
KW - Faculty of Science
KW - COVID-19
KW - Immunity
KW - Diabetes mellitus
KW - Nutrition
KW - Protein
KW - Carbohydrate
KW - Selenium
U2 - 10.1007/s40200-021-00784-5
DO - 10.1007/s40200-021-00784-5
M3 - Review
C2 - 33842400
VL - 20
SP - 963
EP - 972
JO - Journal of Diabetes and Metabolic Disorders
JF - Journal of Diabetes and Metabolic Disorders
SN - 2251-6581
IS - 1
ER -
ID: 259505277