Cavity-enhanced optical frequency combspectroscopy: Application to human breathanalysis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cavity-enhanced optical frequency combspectroscopy : Application to human breathanalysis. / Balslev-Clausen, David Morten; Thorpe, M. J.; Kirchner, M. S.; Ye, J.

In: Optics Express, Vol. 16, No. 4, 2008, p. 2387-2397.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Balslev-Clausen, DM, Thorpe, MJ, Kirchner, MS & Ye, J 2008, 'Cavity-enhanced optical frequency combspectroscopy: Application to human breathanalysis', Optics Express, vol. 16, no. 4, pp. 2387-2397. https://doi.org/10.1364/OE.16.002387

APA

Balslev-Clausen, D. M., Thorpe, M. J., Kirchner, M. S., & Ye, J. (2008). Cavity-enhanced optical frequency combspectroscopy: Application to human breathanalysis. Optics Express, 16(4), 2387-2397. https://doi.org/10.1364/OE.16.002387

Vancouver

Balslev-Clausen DM, Thorpe MJ, Kirchner MS, Ye J. Cavity-enhanced optical frequency combspectroscopy: Application to human breathanalysis. Optics Express. 2008;16(4):2387-2397. https://doi.org/10.1364/OE.16.002387

Author

Balslev-Clausen, David Morten ; Thorpe, M. J. ; Kirchner, M. S. ; Ye, J. / Cavity-enhanced optical frequency combspectroscopy : Application to human breathanalysis. In: Optics Express. 2008 ; Vol. 16, No. 4. pp. 2387-2397.

Bibtex

@article{aa094a9001a911deb05e000ea68e967b,
title = "Cavity-enhanced optical frequency combspectroscopy: Application to human breathanalysis",
abstract = "Broad-bandwidth, high-spectral-resolution optical detection of human breath has identified multiple important biomarkers correlated with specific diseases and metabolic processes. This optical-frequency-comb-based breath analysis system comes with excellent performance in all criteria: high detection sensitivity, ability to identify and distinguish a large number of analytes, and simultaneous, real-time information processing. We demonstrate a minimum detectable absorption of 8 x 10-10cm-1, a spectral resolution of 800 MHz, and 200 nm of spectral coverage from 1.5 to 1.7 µm where strong and unique molecular fingerprints exist for many biomarkers. We present a series of breath measurements including stable isotope ratios of CO2, breath concentrations of CO, and the presence of trace concentrations of NH3 in high concentrations of H2O. Udgivelsesdato: 02.05",
author = "Balslev-Clausen, {David Morten} and Thorpe, {M. J.} and Kirchner, {M. S.} and J. Ye",
year = "2008",
doi = "10.1364/OE.16.002387",
language = "English",
volume = "16",
pages = "2387--2397",
journal = "Optics Express",
issn = "1094-4087",
publisher = "The Optical Society",
number = "4",

}

RIS

TY - JOUR

T1 - Cavity-enhanced optical frequency combspectroscopy

T2 - Application to human breathanalysis

AU - Balslev-Clausen, David Morten

AU - Thorpe, M. J.

AU - Kirchner, M. S.

AU - Ye, J.

PY - 2008

Y1 - 2008

N2 - Broad-bandwidth, high-spectral-resolution optical detection of human breath has identified multiple important biomarkers correlated with specific diseases and metabolic processes. This optical-frequency-comb-based breath analysis system comes with excellent performance in all criteria: high detection sensitivity, ability to identify and distinguish a large number of analytes, and simultaneous, real-time information processing. We demonstrate a minimum detectable absorption of 8 x 10-10cm-1, a spectral resolution of 800 MHz, and 200 nm of spectral coverage from 1.5 to 1.7 µm where strong and unique molecular fingerprints exist for many biomarkers. We present a series of breath measurements including stable isotope ratios of CO2, breath concentrations of CO, and the presence of trace concentrations of NH3 in high concentrations of H2O. Udgivelsesdato: 02.05

AB - Broad-bandwidth, high-spectral-resolution optical detection of human breath has identified multiple important biomarkers correlated with specific diseases and metabolic processes. This optical-frequency-comb-based breath analysis system comes with excellent performance in all criteria: high detection sensitivity, ability to identify and distinguish a large number of analytes, and simultaneous, real-time information processing. We demonstrate a minimum detectable absorption of 8 x 10-10cm-1, a spectral resolution of 800 MHz, and 200 nm of spectral coverage from 1.5 to 1.7 µm where strong and unique molecular fingerprints exist for many biomarkers. We present a series of breath measurements including stable isotope ratios of CO2, breath concentrations of CO, and the presence of trace concentrations of NH3 in high concentrations of H2O. Udgivelsesdato: 02.05

U2 - 10.1364/OE.16.002387

DO - 10.1364/OE.16.002387

M3 - Journal article

VL - 16

SP - 2387

EP - 2397

JO - Optics Express

JF - Optics Express

SN - 1094-4087

IS - 4

ER -

ID: 10732362