Iminolactones from Schizophyllum commune
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Iminolactones from Schizophyllum commune. / Liu, Xuemei; Frydenvang, Karla Andrea; Liu, Huizhen; Zhai, Lin; Chen, Ming; Olsen, Carl Erik; Christensen, Søren Brøgger.
In: Journal of Natural Products, Vol. 78, No. 5, 2015, p. 1165-1168.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Iminolactones from Schizophyllum commune
AU - Liu, Xuemei
AU - Frydenvang, Karla Andrea
AU - Liu, Huizhen
AU - Zhai, Lin
AU - Chen, Ming
AU - Olsen, Carl Erik
AU - Christensen, Søren Brøgger
PY - 2015
Y1 - 2015
N2 - Schizine A (1) and B (2) the first naturally occurring iminolactones (3,6-dihydro-2H-1,4-oxazin-2-one derivatives) to be reported have been isolated from the fruiting bodies of Schizophyllym commune. In principle the 2-oxazinone moiety might have been formed by a reaction between the amino acids phenylalanine or tryptophan and an α-hydroxyketomniopetal. The alkaloids are unusual in that the carboxyl group of the amino acid precursor is preserved during the biosynthesis. The compounds showed some inhibition of the growth of cancer cells.
AB - Schizine A (1) and B (2) the first naturally occurring iminolactones (3,6-dihydro-2H-1,4-oxazin-2-one derivatives) to be reported have been isolated from the fruiting bodies of Schizophyllym commune. In principle the 2-oxazinone moiety might have been formed by a reaction between the amino acids phenylalanine or tryptophan and an α-hydroxyketomniopetal. The alkaloids are unusual in that the carboxyl group of the amino acid precursor is preserved during the biosynthesis. The compounds showed some inhibition of the growth of cancer cells.
KW - Faculty of Health and Medical Sciences
KW - Natural products
KW - Iminolactones
KW - Schizophyllum commune
U2 - 10.1021/np500836y
DO - 10.1021/np500836y
M3 - Journal article
C2 - 25951057
VL - 78
SP - 1165
EP - 1168
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0974-5211
IS - 5
ER -
ID: 137476779