Mentalization-based treatment in groups for adolescents with Borderline Personality Disorder: 3- and 12-month follow-up of a randomized controlled trial
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Mentalization-based treatment in groups for adolescents with Borderline Personality Disorder : 3- and 12-month follow-up of a randomized controlled trial. / Jørgensen, Mie Sedoc; Storebø, Ole Jakob; Bo, Sune; Poulsen, Stig; Gondan, Matthias; Beck, Emma; Chanen, Andrew M; Bateman, Anthony; Pedersen, Jesper; Simonsen, Erik.
In: European Child & Adolescent Psychiatry, Vol. 30, 2021, p. 699–710.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Mentalization-based treatment in groups for adolescents with Borderline Personality Disorder
T2 - 3- and 12-month follow-up of a randomized controlled trial
AU - Jørgensen, Mie Sedoc
AU - Storebø, Ole Jakob
AU - Bo, Sune
AU - Poulsen, Stig
AU - Gondan, Matthias
AU - Beck, Emma
AU - Chanen, Andrew M
AU - Bateman, Anthony
AU - Pedersen, Jesper
AU - Simonsen, Erik
PY - 2021
Y1 - 2021
N2 - Mentalization-based treatment in groups (MBT-G) has never been tested in adolescents with Borderline Personality Disorder (BPD) in a randomized controlled trial. The current study aimed to test the long-term effectiveness of MBT-G in an adolescent sample with BPD or BPD features (≥ 4 DSM-5 BPD criteria). Hundred and eleven patients with BPD (n = 106) or BPD features (n = 5) were randomized to either (1) a 1-year modified MBT-G program comprising three MBT introductory sessions, five individual case formulation sessions, 37 weekly MBT group sessions, and six MBT-Parent sessions, or (2) treatment as usual (TAU), defined as at least 12 individual monthly treatment sessions with follow-up assessments at 3 and 12 months post treatment. The primary outcome was the score on the Borderline Personality Features Scale for Children (BPFS-C), and secondary outcomes included clinician-rated BPD symptoms and global level of functioning as well as self-reported self-harm, depression, externalizing and internalizing symptoms, and caregiver reports. There were no statistically significant differences between MBT-G and TAU on the primary outcome measure or any of the secondary outcomes. Both groups showed improvement on the majority of clinical and social outcomes at both follow-up points, although remission rates were modest with just 35% in MBT-G and 39% in TAU 2 years after inclusion into the study. MBT-G was not superior to TAU in improving borderline features in adolescents. Although improvement was observed equally in both interventions over time, the patients continued to exhibit prominent BPD features, general psychopathology and decreased functioning in the follow-up period, which points to a need for more research and better understanding of effective components in early intervention programs. The ClinicalTrials.gov identifier is NCT02068326.
AB - Mentalization-based treatment in groups (MBT-G) has never been tested in adolescents with Borderline Personality Disorder (BPD) in a randomized controlled trial. The current study aimed to test the long-term effectiveness of MBT-G in an adolescent sample with BPD or BPD features (≥ 4 DSM-5 BPD criteria). Hundred and eleven patients with BPD (n = 106) or BPD features (n = 5) were randomized to either (1) a 1-year modified MBT-G program comprising three MBT introductory sessions, five individual case formulation sessions, 37 weekly MBT group sessions, and six MBT-Parent sessions, or (2) treatment as usual (TAU), defined as at least 12 individual monthly treatment sessions with follow-up assessments at 3 and 12 months post treatment. The primary outcome was the score on the Borderline Personality Features Scale for Children (BPFS-C), and secondary outcomes included clinician-rated BPD symptoms and global level of functioning as well as self-reported self-harm, depression, externalizing and internalizing symptoms, and caregiver reports. There were no statistically significant differences between MBT-G and TAU on the primary outcome measure or any of the secondary outcomes. Both groups showed improvement on the majority of clinical and social outcomes at both follow-up points, although remission rates were modest with just 35% in MBT-G and 39% in TAU 2 years after inclusion into the study. MBT-G was not superior to TAU in improving borderline features in adolescents. Although improvement was observed equally in both interventions over time, the patients continued to exhibit prominent BPD features, general psychopathology and decreased functioning in the follow-up period, which points to a need for more research and better understanding of effective components in early intervention programs. The ClinicalTrials.gov identifier is NCT02068326.
KW - Faculty of Social Sciences
KW - Mentalization-based treatment
KW - Mentalizing
KW - Adolescence
KW - Borderline Personality Disorder
KW - Group psychotherapy
KW - Follow-up
U2 - 10.1007/s00787-020-01551-2
DO - 10.1007/s00787-020-01551-2
M3 - Journal article
C2 - 32388627
VL - 30
SP - 699
EP - 710
JO - European Child and Adolescent Psychiatry, Supplement
JF - European Child and Adolescent Psychiatry, Supplement
SN - 1433-5719
ER -
ID: 241089799