Julius Bier Kirkegaard

Julius Bier Kirkegaard

Assistant Professor, Tenure Track Assistant Professor


  1. Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.

    Meisl, G., Yang, X., Hellstrand, E., Frohm, B., Kirkegaard, Julius Bier, Cohen, S., Dobson, C., Linse, S. & Knowles, T., Jun 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, p. 9384-9389 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Molecular mechanisms of protein aggregation from global fitting of kinetic models.

    Meisl, G., Kirkegaard, Julius Bier, Arosio, P., Michaels, T., Vendruscolo, M., Dobson, C., Linse, S. & Knowles, T., Jan 2016, In: Nature Protocols. 11, p. 252-272 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Fluctuations in the Kinetics of Linear Protein Self-Assembly.

    Michaels, T., Dear, A., Kirkegaard, Julius Bier, Saar, K., Weitz, D. & Knowles, T., Jun 2016, In: Physical Review Letters. 116, 5 p., 258103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Fluctuations in the Kinetics of Linear Protein Self-Assembly.

    Michaels, T., Dear, A., Kirkegaard, Julius Bier, Saar, K. L., Weitz, D. A. & Knowles, T., 23 Aug 2019, In: Apollo - University of Cambridge Repository. 116, 25, p. 258103-258103 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

    Perni, M., Galvagnion, C., Maltsev, A., Meisl, G., Müller, M. B. D., Challa, P. K., Kirkegaard, J. B., Flagmeier, P., Cohen, S. I. A., Cascella, R., Chen, S. W., Limbocker, R., Sormanni, P., Heller, G. T., Aprile, F. A., Cremades, N., Cecchi, C., Chiti, F., Nollen, E. A. A., Knowles, T. P. J. & 4 others, Vendruscolo, M., Bax, A., Zasloff, M. & Dobson, C. M., 7 Feb 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. E1009-E1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Epigenetic switching with asymmetric bridging interactions

    Skjegstad, L. E. J., Nickels, Jan Fabio, Sneppen, Kim & Kirkegaard, Julius Bier, 20 Jun 2023, In: Biophysical Journal. 122, 12, p. 2421-2429 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers.

    Varilly, P., Willard, A., Kirkegaard, Julius Bier, Knowles, T. & Chandler, D., Apr 2017, In: The Journal of Chemical Physics. 146, 5 p., 135102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.

    perni, M., challa, P. K., Kirkegaard, Julius Bier, Limbocker, R., Koopman, M., Hardenberg, M. C., Sormanni, P., Müller, T., Saar, K. L., Roode, L. W., Habchi, J., Vecchi, G., Fernando, N., Casford, S., Nollen, E. A., Vendruscolo, M., Dobson, C. & Knowles, T., 27 Jul 2018, In: Apollo - University of Cambridge Repository. 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.

    perni, M., Flagmeier, P., Limbocker, R., Cascella, R., Aprile, F. A., Galvagnion, C., Heller, G. T., Meisl, G., Chen, S. W., Kumita, J., challa, P. K., Kirkegaard, J., Cohen, S. IA., Mannini, B., Barbut, D., Nollen, E. AA., Cecchi, C., Casasin, N. C., Knowles, T., Chiti, F. & 3 others, Zasloff, M., Vendruscolo, M. & Dobson, C. M., 18 Jul 2019, In: Apollo - University of Cambridge Repository.

    Research output: Contribution to journalJournal articleResearchpeer-review

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