Genes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli

Research output: Contribution to journalJournal articleResearchpeer-review

4.5S RNAs of eubacteria and 7S RNAs of archaebacteria and eukaryotes exist in a hairpin conformation. The apex of this hairpin displays structural and sequence similarities among both 4.5S and 7S RNAs. Furthermore, a hyphenated sequence of 16 nucleotides is conserved in all eubacterial 4.5S RNAs examined. In this article I report that 7S RNAs that contain this 16-nucleotide sequence are able to replace 4.5S RNAs and permit growth of Escherichia coli.
Original languageEnglish
JournalJournal of Bacteriology
Volume173
Issue number5
Pages (from-to)1835-7
Number of pages2
ISSN0021-9193
Publication statusPublished - 1991

Bibliographical note

Keywords: Base Sequence; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Models, Structural; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; RNA, Ribosomal

ID: 9298316