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A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis. / Huynh, Tri H V; Mantel, Mette Louise H; Mikkelsen, Katrine; Lindhardt, Anders T; Nielsen, Niels Chr; Otzen, Daniel; Skrydstrup, Troels.
In:
Organic Letters, Vol. 11, No. 4, 19.02.2009, p. 999-1002.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Huynh, THV, Mantel, MLH, Mikkelsen, K, Lindhardt, AT, Nielsen, NC, Otzen, D & Skrydstrup, T 2009, '
A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis',
Organic Letters, vol. 11, no. 4, pp. 999-1002.
https://doi.org/10.1021/ol8029593
APA
Huynh, T. H. V., Mantel, M. L. H., Mikkelsen, K., Lindhardt, A. T., Nielsen, N. C., Otzen, D., & Skrydstrup, T. (2009).
A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis.
Organic Letters,
11(4), 999-1002.
https://doi.org/10.1021/ol8029593
Vancouver
Huynh THV, Mantel MLH, Mikkelsen K, Lindhardt AT, Nielsen NC, Otzen D et al.
A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis.
Organic Letters. 2009 Feb 19;11(4):999-1002.
https://doi.org/10.1021/ol8029593
Author
Huynh, Tri H V ; Mantel, Mette Louise H ; Mikkelsen, Katrine ; Lindhardt, Anders T ; Nielsen, Niels Chr ; Otzen, Daniel ; Skrydstrup, Troels. / A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis. In: Organic Letters. 2009 ; Vol. 11, No. 4. pp. 999-1002.
Bibtex
@article{429853f6ef944259849fbb649a34e3d1,
title = "A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis",
abstract = "Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of beta-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer, and (19)F-BAY94-9172.",
keywords = "Alkenes/chemical synthesis, Alkynes/chemistry, Amyloid beta-Peptides/metabolism, Aniline Compounds/chemical synthesis, Molecular Structure, Protein Binding, Stereoisomerism, Stilbenes/chemical synthesis, Styrenes/chemical synthesis",
author = "Huynh, {Tri H V} and Mantel, {Mette Louise H} and Katrine Mikkelsen and Lindhardt, {Anders T} and Nielsen, {Niels Chr} and Daniel Otzen and Troels Skrydstrup",
year = "2009",
month = feb,
day = "19",
doi = "10.1021/ol8029593",
language = "English",
volume = "11",
pages = "999--1002",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "4",
}
RIS
TY - JOUR
T1 - A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis
AU - Huynh, Tri H V
AU - Mantel, Mette Louise H
AU - Mikkelsen, Katrine
AU - Lindhardt, Anders T
AU - Nielsen, Niels Chr
AU - Otzen, Daniel
AU - Skrydstrup, Troels
PY - 2009/2/19
Y1 - 2009/2/19
N2 - Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of beta-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer, and (19)F-BAY94-9172.
AB - Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of beta-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer, and (19)F-BAY94-9172.
KW - Alkenes/chemical synthesis
KW - Alkynes/chemistry
KW - Amyloid beta-Peptides/metabolism
KW - Aniline Compounds/chemical synthesis
KW - Molecular Structure
KW - Protein Binding
KW - Stereoisomerism
KW - Stilbenes/chemical synthesis
KW - Styrenes/chemical synthesis
U2 - 10.1021/ol8029593
DO - 10.1021/ol8029593
M3 - Journal article
C2 - 19161320
VL - 11
SP - 999
EP - 1002
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 4
ER -
